National Institute On Aging (nia)

This study tests whether urolithin A, a natural supplement, can improve how the body releases insulin and controls blood sugar in healthy adults aged 55 and older with a BMI of 27 or higher. Over 8 weeks, 180 participants will take either urolithin A or a placebo daily. Researche…

This study explores whether stem cells from taste buds can be turned into insulin-making cells. Researchers will take tiny tissue samples from the tongues of 250 healthy adults to isolate and grow these stem cells in a lab. The goal is to see if this is possible in humans, which …

This study uses yearly PET scans to track amyloid protein buildup in the brains of 400 adults aged 55 and older over 5 years. Participants are already part of the Baltimore Longitudinal Study of Aging. The goal is to see how these brain changes relate to memory loss and other thi…

This study collects white blood cells from healthy volunteers using a procedure called cytapheresis. The cells are used for lab research, not to treat any disease. Participants must be 18 or older and can donate every 56 days.

This study collects tissue samples like blood, urine, skin, and fat from both healthy volunteers and people with certain conditions. The goal is to give researchers the materials they need to better understand diseases and design future studies. Up to 5,000 adults aged 18 and old…

The GESTALT study is recruiting 900 adults aged 20 and older to investigate biomarkers related to aging. Participants will undergo a range of tests every two years, including blood work, imaging, and physical exams. The goal is to better understand how genetic and epigenetic chan…

This study aims to find the genetic causes of movement disorders and dementias by analyzing DNA from up to 12,000 participants, including patients and their family members. Researchers will collect blood or saliva samples and look for gene mutations linked to these conditions. Th…

This study, running since 1958, follows healthy adults aged 20 and older for life to understand how people age. Participants undergo physical exams, cognitive tests, imaging, and other assessments every few years. The goal is to characterize the aging process and learn how people…

This study aims to develop and improve MRI scanning techniques for use in aging research. Healthy adults and individuals with certain conditions will undergo MRI scans, sometimes with contrast agents or while performing tasks. No treatment is given; the goal is to refine imaging …

This study collects bone marrow samples from healthy adults aged 18 and older to understand how blood-forming cells change as we age. Participants provide a sample every two years, along with physical exams and blood tests. The cells are used for genetic research only, not for tr…

This study will use advanced MRI scans to look at how the brain's white matter changes as children go through puberty. Researchers will enroll 80 healthy kids aged 9 to 14 and track their physical development alongside brain imaging. The goal is to better understand normal brain …

This study looks at how quickly proteins in the body are replaced, a process called protein turnover, in healthy adults aged 20 and older. Participants drink heavy water for 21 days and undergo tests including muscle, skin, and fat biopsies, imaging scans, and strength tests. The…