National Institute On Aging (nia)

This study collects bone marrow samples from healthy adults aged 18 and older to learn how blood-forming cells change as we age. Participants provide a sample every two years. The goal is to understand normal aging, not to treat any disease.

This study aims to improve MRI scanning methods used in aging research. Researchers will test and refine imaging techniques on healthy adults and people with certain health conditions. Participants undergo MRI scans, sometimes with contrast agents or while performing simple tasks…

This study uses yearly PET scans to track amyloid proteins in the brains of 400 adults aged 55 and older over 5 years. Researchers aim to understand how these proteins build up with age and whether they are linked to memory loss or other thinking problems. Participants also take …

This study looks for genetic causes of movement disorders (like tremors or stiffness) and dementia (memory loss). Researchers will collect blood or saliva from up to 12,000 people, including patients and their family members, as well as healthy volunteers. The goal is to better u…

This study looks at substances in blood and tissues called biomarkers to better understand aging. Researchers will follow 900 healthy and frail adults over many years, collecting samples and doing tests. The goal is to find ways to improve quality of life as people get older.

This study aims to learn how the brain changes as children go through puberty. Researchers will use MRI scans and other tests to look at brain structure in healthy kids aged 9 to 14. The goal is to better understand normal brain development during this important time. No treatmen…

This study aims to understand how people age by following healthy volunteers for life. Participants aged 20 and older undergo physical and mental tests every few years. The goal is to learn how people can adapt to aging successfully.

This study tests whether urolithin A, a natural supplement, can improve how the body controls blood sugar in healthy adults aged 55 and older with a higher body mass index. Researchers will measure insulin and other hormone levels after taking the supplement for 4 and 8 weeks. Th…

This study collects white blood cells from healthy volunteers using a procedure called cytapheresis. The cells are used for lab research only, not to treat any disease. Participants must be at least 18 years old and can donate up to six times per year.

This study collects tissue samples (like blood, skin, and fat) from 5,000 healthy volunteers and people with certain conditions. The samples are used for research only, not for treating participants. The goal is to help scientists better understand diseases and develop new ways t…

This study aims to see if stem cells from taste buds can be turned into insulin-producing cells, which could lead to new diabetes treatments. Researchers will take tiny tissue samples from the tongues of 250 healthy adults. The goal is to grow these cells in a lab and test if the…

This study aims to measure how quickly proteins in the body are replaced (protein turnover) in healthy adults of different ages. Participants will drink small amounts of safe heavy water for 21 days and undergo tests including muscle and fat biopsies, imaging scans, and strength …