National Cancer Institute, Naples

This study tests a drug called Inavolisib in about 48 women with advanced endometrial cancer that has a specific change in the PIK3CA gene. The goal is to see if the drug can shrink tumors or slow cancer growth. Participants will take the drug and be monitored for response and si…

This study tests whether artificial intelligence can guide how much fluid patients receive during major cancer surgery to keep their blood pressure more stable. About 176 adults having long cancer operations will be randomly assigned to either AI-guided fluid management or standa…

This study tests whether adding a balanced THC/CBD cannabis extract to standard pain treatment can reduce symptom burden in 156 adults with advanced solid tumors. Participants will receive either the cannabis extract or a placebo for 8 weeks, and researchers will measure changes …

This study looks at how well a special type of surgery that removes cancer along with affected blood vessels works for people with advanced gynecologic cancers. Researchers will track 130 patients over 5 years to see how long they live and how long it takes for the cancer to come…