Montefiore Medical Center
Clinical trials sponsored by Montefiore Medical Center, explained in plain language.
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HPV vaccine shields High-Risk women for years, new study shows
⭐️ VACCINE ⭐️ CompletedThis study looked at how well the HPV vaccine protects Rwandan women aged 18-28, both with and without HIV, from HPV infections that can cause cancer. Researchers measured infections and immune responses years after vaccination. The goal is to confirm long-term protection and tes…
Sponsor: Montefiore Medical Center • Aim: ⭐️ VACCINE ⭐️
Last updated May 01, 2026 16:01 UTC
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Group therapy boosts quit rates in HIV smokers
Disease control CompletedThis study tested a group therapy program called Positively Smoke Free for people living with HIV who want to quit smoking. Researchers compared it to standard care in 450 participants. The main goal was to see if the program helped more people stay smoke-free for 6 months.
Phase: NA • Sponsor: Montefiore Medical Center • Aim: Disease control
Last updated Apr 30, 2026 15:51 UTC
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Targeted radiation zaps liver tumors without surgery
Disease control CompletedThis small pilot study tested a high-precision radiation technique called stereotactic body radiation therapy (SBRT) in 20 adults with liver cancer that could not be surgically removed. The goal was to see if this approach could safely deliver radiation directly to the tumor whil…
Phase: NA • Sponsor: Montefiore Medical Center • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
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Prostate cancer patients may ditch painful hormone shots with new pill combo
Disease control CompletedThis study looked at whether men with advanced prostate cancer can safely stop their regular hormone injections (like leuprolide) while continuing to take abiraterone and prednisone pills. The goal was to see if testosterone levels would stay low enough without the shots. 31 men …
Phase: PHASE2 • Sponsor: Montefiore Medical Center • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
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School program gives asthmatic kids more Symptom-Free days
Disease control CompletedThis study tested a school-based program to help children with asthma be more physically active and have fewer asthma symptoms. It included 452 children with asthma. The program aimed to remove barriers to exercise and improve asthma control.
Phase: NA • Sponsor: Montefiore Medical Center • Aim: Disease control
Last updated Apr 29, 2026 15:11 UTC
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New combo therapy shows promise for tough lung cancers
Disease control CompletedThis study tested a new treatment for people with advanced non-small cell lung cancer that had stopped responding to standard therapies. Participants received daily injections of an immune-boosting drug (FLT3 ligand) for five days along with precise, high-dose radiation to one tu…
Phase: PHASE2 • Sponsor: Montefiore Medical Center • Aim: Disease control
Last updated Apr 29, 2026 15:05 UTC
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Syringe exchange clinics offer on-the-spot addiction meds, study finds better engagement
Disease control CompletedThis study tested whether giving buprenorphine (a medication for opioid addiction) directly at syringe exchange programs helps people stay in treatment better than sending them to a separate clinic. 97 syringe exchange participants with opioid addiction were enrolled. The main go…
Phase: PHASE2 • Sponsor: Montefiore Medical Center • Aim: Disease control
Last updated Apr 29, 2026 15:02 UTC
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VR goggles take the ouch out of blood draws for kids
Symptom relief CompletedThis study tested whether virtual reality (VR) goggles could distract children ages 5-21 during a blood draw, reducing their pain and anxiety. Half of the 126 hospitalized children received standard care (numbing cream), while the other half also wore VR goggles. Researchers meas…
Phase: NA • Sponsor: Montefiore Medical Center • Aim: Symptom relief
Last updated May 01, 2026 16:01 UTC
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Walk your way through cancer treatment: study tests simple step plan
Symptom relief CompletedThis study tested whether a simple walking program, using fitness trackers, helps people with certain cancers (brain, head and neck, lung, gastrointestinal, or cervical) complete their daily radiation and chemotherapy without missing treatments. 166 adults who could walk without …
Phase: NA • Sponsor: Montefiore Medical Center • Aim: Symptom relief
Last updated May 01, 2026 16:01 UTC
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Nerve block slashes opioid need after breast surgery
Symptom relief CompletedThis study tested whether adding a nerve block to standard pain management could lower the amount of strong painkillers (opioids) needed after breast reduction surgery. 78 adults took part. The goal was to see if the block helps control pain and reduces side effects like nausea, …
Phase: NA • Sponsor: Montefiore Medical Center • Aim: Symptom relief
Last updated May 01, 2026 16:00 UTC
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Sleep aid melatonin may cut painkiller need after wisdom tooth removal
Symptom relief CompletedThis study tested if taking melatonin for three nights before wisdom tooth surgery can lower pain and the amount of pain medication needed afterward. Sixty adults aged 18-35 took either melatonin or a placebo before their surgery. Researchers measured how many pain pills they use…
Phase: PHASE2 • Sponsor: Montefiore Medical Center • Aim: Symptom relief
Last updated Apr 30, 2026 15:49 UTC
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Step counts predict hospital stays: new study tests pedometer alerts
Symptom relief CompletedThis study tested whether tracking daily steps with a simple pedometer could help doctors spot cancer patients who are at risk of being hospitalized during chemoradiotherapy. 40 adults with head and neck, lung, esophagus, or stomach cancer wore a step counter. If their step count…
Phase: NA • Sponsor: Montefiore Medical Center • Aim: Symptom relief
Last updated Apr 29, 2026 15:05 UTC
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Art as medicine: study tests DIY art for pain and opioid misuse
Symptom relief CompletedThis study looked at whether people with chronic pain and opioid use disorder would regularly do art on their own at home. 31 adults tried self-directed artmaking and reported how it affected their pain, mood, and anxiety. The goal was to see if this simple, drug-free activity is…
Phase: NA • Sponsor: Montefiore Medical Center • Aim: Symptom relief
Last updated Apr 29, 2026 15:03 UTC
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Meditation app may ease Post-Surgery pain
Symptom relief CompletedThis study tested whether using the Headspace meditation app before surgery could help reduce pain after a minimally invasive hysterectomy. 72 women participated. The goal was to see if mindfulness training could lower pain scores the day after surgery.
Phase: NA • Sponsor: Montefiore Medical Center • Aim: Symptom relief
Last updated Apr 29, 2026 15:02 UTC
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Bronx dads get support to be better parents
Knowledge-focused CompletedThis study tested a program called HERO Dads for low-income fathers in the Bronx who do not live with their children. The program offered classes on parenting, relationships, anger management, and job skills. Researchers measured how involved fathers became with their children af…
Phase: NA • Sponsor: Montefiore Medical Center • Aim: Knowledge-focused
Last updated May 01, 2026 17:42 UTC
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Can zoom strengthen families? bronx study tests virtual relationship coaching for low-income couples
Knowledge-focused CompletedThis study tested whether a virtual relationship skills program helps low-income couples in the Bronx improve their relationship and parenting. Over 1,000 couples took part, learning skills via Zoom. The goal was to see if the program boosts relationship satisfaction and family s…
Phase: NA • Sponsor: Montefiore Medical Center • Aim: Knowledge-focused
Last updated May 01, 2026 16:00 UTC
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Can bias training improve End-of-Life care for black patients?
Knowledge-focused CompletedThis study looked at how doctors' unconscious racial biases affect their communication with Black family members during end-of-life care. Twenty-two doctors participated in simulated conversations with actors playing family members. Some doctors received special training to reduc…
Phase: NA • Sponsor: Montefiore Medical Center • Aim: Knowledge-focused
Last updated May 01, 2026 16:00 UTC
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AI showdown: which tool helps doctors think better?
Knowledge-focused CompletedThis study tested two AI tools—Clinical Key AI and GPT-4—to see which one helps doctors make better diagnoses and treatment choices. 27 internal medicine doctors and residents participated. The goal was to learn how these tools affect clinical reasoning, not to treat a disease.…
Phase: NA • Sponsor: Montefiore Medical Center • Aim: Knowledge-focused
Last updated May 01, 2026 15:57 UTC
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Smart mat could predict foot ulcers before they start
Knowledge-focused CompletedThis study tested whether people with diabetes would regularly use a special foot mat that detects temperature changes, which can signal an upcoming foot ulcer. Twenty adults who had a diabetic foot ulcer in the past used the FDA-cleared Podimetrics Smart Mat at home for six mont…
Phase: NA • Sponsor: Montefiore Medical Center • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:03 UTC
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Can a special diet help kidney patients? small study says maybe
Knowledge-focused CompletedThis pilot study looked at whether a culturally-tailored anti-inflammatory diet is practical and well-liked by racial/ethnic minorities with chronic kidney disease. 18 adults from the Bronx took part. The goal was to see if people could stick with the diet and if it reduced infla…
Phase: NA • Sponsor: Montefiore Medical Center • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:03 UTC