Memorial Sloan Kettering Cancer Center

This study tests a combination of four drugs (carfilzomib, lenalidomide, dexamethasone, and daratumumab) given before and after a stem cell transplant for people whose multiple myeloma has returned after prior treatment. The goal is to see if this intensive approach can lead to c…

This study tests whether combining two drugs, pembrolizumab and lenvatinib, can shrink tumors or slow cancer growth in people with advanced uterine or ovarian carcinosarcoma, a rare and aggressive cancer. About 40 participants will receive the treatment, and researchers will also…

This early-phase study tests whether giving targeted radiation before standard CAR T-cell therapy is safe and practical for people with relapsed or refractory B-cell lymphoma. About 20 participants will receive radiation to all active disease sites before their CAR T infusion. Th…

This study tests a drug called amivantamab in 25 people with a specific type of stomach or esophagus cancer that has a change in the EGFR or MET gene. The goal is to see if the drug can shrink tumors and is safe. Participants must have already tried at least one other treatment.

This early-stage study tests a combination of three drugs—belantamab mafodotin, nirogacestat, and pomalidomide—in people whose multiple myeloma has returned or stopped responding to prior treatments. The main goal is to find the safest dose and see if the combination can slow or …

This study tests whether adding blinatumomab to standard targeted therapy (TKI) can better treat adults with a specific type of leukemia (Ph+ ALL). About 17 participants will receive the drug combination after initial treatment. The goal is to see if more patients achieve a deep …

This study tests whether a drug called PDR001, combined with either trametinib or dabrafenib, is safe and effective for people with thyroid cancer that no longer responds to standard radioactive iodine treatment. The trial enrolled 19 adults whose cancer had worsened. The main go…

This study looks at whether a community education program, with or without text message reminders, can help more Mexican-American parents complete the HPV vaccine series for their children aged 11 to 17. About 672 parents who speak Spanish and have a child who hasn't finished the…

This study looks at whether using an interactive 3D tool during a surgical consultation helps women with breast cancer feel more satisfied with the information they receive about breast reconstruction options. About 88 women planning mastectomy will take part. Researchers will me…

This study tests whether acupuncture can improve memory, concentration, and sleep problems in 270 breast cancer survivors. Participants receive either real acupuncture, placebo acupuncture, or no acupuncture, and complete questionnaires over 26 weeks. The goal is to see if acupun…

This study looks at whether giving methadone during spinal surgery for cancer patients helps control pain better than standard pain medications in the first 72 hours after surgery. About 17 adults having spine surgery will be randomly assigned to receive either methadone or usual…

This study is creating large registries for non-communicable diseases (like heart disease and cancer) in sub-Saharan Africa. Researchers will collect health data and stool samples from nearly 7,000 adults, including healthy volunteers, to better understand these diseases and impr…

This study looks at how often cancer patients with risk factors like diabetes or smoking have peripheral arterial disease (PAD), a condition that narrows blood vessels. Researchers will test 114 patients before major surgery to find undiagnosed PAD and compare rates across racial…

This study looks at whether tooth enamel loss (dental erosion) can be a simple, non-invasive clue for detecting esophagogastric and other cancers. Researchers will compare dental erosion in 174 people with various cancers and healthy volunteers. The goal is to understand how comm…

This study is testing new guidelines for reading PET scans in people with neuroendocrine tumors. The goal is to see if these new criteria can more accurately predict whether a person's cancer improves, worsens, or stays the same after treatment. About 11 participants who are alre…

This study looks back at the medical records of 250 sarcoma patients who received immunotherapy at Memorial Sloan Kettering Cancer Center. The goal is to gather information and better understand how well these treatments work. No new treatments are given; the study simply collect…

This study looks at how well sentinel lymph node biopsy finds leftover cancer cells after chemotherapy in women with locally advanced breast cancer. About 162 women who had chemotherapy and whose lymph nodes seemed cancer-free will get this biopsy. The goal is to see how often th…