Can acupuncture sharpen a cancer Survivor's mind?
NCT ID NCT04837820
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether acupuncture can improve thinking problems (like memory and focus) in breast cancer survivors. About 270 women who have finished cancer treatment will receive either real acupuncture, sham acupuncture, or standard care. Researchers will track their cognitive function and sleep quality over 26 weeks to see if acupuncture helps.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- acupuncture
- What this could lead to
- If it works, this could offer a non-drug option to help breast cancer survivors manage memory and concentration problems.
- What could go wrong
- This is a mid-stage trial with 270 participants, so results are not yet proven. The sham acupuncture group helps control for placebo effects, which are common in acupuncture studies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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270 people
The number who actually took part.
- Started
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Apr 2021
- Expected to finish
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Apr 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * English-proficient adult women with a history of stage 0, I, II, or III breast cancer * Free of oncologic disease by clinical examination or history * Moderate or greater CRCD as indicated by a score of "quite a bit" or "very much" on at least one of the two items that specifically assess concentration and memory on the EORTC QLQ-C30 (version 3.0) * Report that cognitive functions worsened since cancer diagnosis by replying "Yes" to all 3 questions * Do you think or feel that your memory or mental ability has gotten worse since your cancer diagnosis? * Do you think your mind isn't as sharp now as it was before your cancer diagnosis? * Do you feel like these problems have made it harder to function on your job or take care of things around the home? * Presence of insomnia symptoms as indicated by a score ≥8 on the ISI134 * Willing to adhere to all study-related procedures, including randomization to one of the 3 possible choices: acupuncture, sham acupuncture, or wait-list control Exclusion Criteria: * Metastatic breast cancer (stage IV) * Less than 1 month since completion of surgery, chemotherapy or radiation therapy * Greater than 10 years since most recent breast cancer diagnosis * Use of acupuncture for sleep or cognitive symptom management within the past 3 months * Diagnosis of Alzheimer's disease, vascular dementia, Parkinson disease, or other organic brain disorder * Score of \>10 indicative of overt dementia on the Blessed Orientation-Memory-Concentration (BOMC)135 * Primary psychiatric disorder not in remission * As per medical record or self-report, history of stroke or head injury requiring visit to the emergency room or hospitalization, with confirmed structural lesion on neuroimaging, persistent cognitive difficulties impacting work or daily life, or required cognitive rehabilitation. * Pre-existing, uncorrectable visual or auditory impairment that would preclude ability to complete the assessments * Initiation or change in hormonal or targeted therapy within the past 4 weeks * Plans to initiate or change hormonal or targeted therapy in the coming 8 weeks * Altered dose of somnogenic medication (e.g. hypnotics, sedatives, antidepressants) in past 8 weeks * Enrolled or plans to enroll on another MSK neurocognitive study * Unable to provide informed consent for himself/herself
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Memorial Sloan Kettering Basking Ridge (Limited Protocol activities)
Basking Ridge, New Jersey, 07920, United States
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Memorial Sloan Kettering Bergen (Limited Protocol Activities)
Montvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Memorial Sloan Kettering Monmouth (Limited Protocol activities)
Middletown, New Jersey, 07748, United States
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Memorial Sloan Kettering Nassau (Limited Protocol Activities)
Uniondale, New York, 11553, United States
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Memorial Sloan Kettering Suffolk- Commack (Limited Protocol Activities)
Commack, New York, 11725, United States
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Memorial Sloan Kettering Westchester (Limited Protocol Activities)
Harrison, New York, 10604, United States
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