Memorial Sloan Kettering Cancer Center

This study tested a combination of Hu3F8 (an antibody) and GM-CSF (an immune booster) along with isotretinoin in 59 children with high-risk neuroblastoma who had achieved their first remission. The goal was to see if this immunotherapy could prevent the cancer from growing back. …

This study tested a drug called vemurafenib (Zelboraf) in 36 people with hairy cell leukemia that had returned or not responded to standard treatments. The goal was to see how well the drug could clear leukemia cells from the blood and what side effects it might cause. Participan…

This study tested whether adding a radioactive drug called Radium-223 to standard targeted radiation (SBRT) helps men whose prostate cancer has returned in a few bone spots but hasn't yet become hormone-resistant. Twelve men participated, receiving either SBRT alone or SBRT plus …

This study looked at ways to help taxi drivers in New York City better manage high blood pressure and lower their cancer risk. Researchers tested different follow-up methods after health fairs, including phone calls and video consults. The goal was to find the best approach to he…

This study tested whether a targeted drug called brentuximab vedotin (SGN-35) could replace the standard ICE chemotherapy before a stem cell transplant for people with Hodgkin lymphoma that came back or didn't go away. 66 patients received two cycles of SGN-35, and PET scans were…

This study tested whether combining two drugs, pembrolizumab and olaparib, can help people with endometrial cancer that has come back or not gone away. The trial included 26 adults with specific types of this cancer. Researchers measured how many participants' tumors shrank and t…

This study tested whether a smaller dose of radiation can control high-risk neuroblastoma while reducing long-term side effects. 78 children with high-risk neuroblastoma received reduced-dose radiation to the tumor site. Researchers tracked tumor response and side effects over ti…

This study tested a new approach for treating multiple myeloma, a type of blood cancer. Instead of giving three strong drugs together from the start, doctors first gave two drugs (bortezomib and dexamethasone). Only if the disease did not respond well was a third drug (lenalidomi…

This early-phase study looked at adding the immunotherapy drugs nivolumab (with or without ipilimumab) to standard chemotherapy for people with advanced high-grade serous ovarian, fallopian tube, or primary peritoneal cancer. The main goal was to see if the combination was safe a…

This study tested whether giving higher doses of the drug carfilzomib, along with two other drugs (lenalidomide and dexamethasone), is safe for people newly diagnosed with multiple myeloma. 29 patients took part to find the best tolerated dose and to see how many cancer cells rem…

This early-phase study tested the safety of combining two targeted drugs, dacomitinib and osimertinib, for people with a specific type of advanced lung cancer (EGFR mutant) that had not been treated with similar drugs before. The goal was to find the safest dose and see how well …

This early-phase trial tested a combination of three drugs (ibrutinib, rituximab, and lenalidomide) in 25 adults with recurrent or treatment-resistant central nervous system lymphoma. The main goal was to find the safest dose of ibrutinib when given with the other two drugs. Rese…

This study tested the safety and effectiveness of combining two targeted drugs, copanlisib and ibrutinib, in 18 adults with primary CNS lymphoma that had returned or not responded to prior treatment. The goal was to find the best dose and see how many patients' tumors shrank. Thi…

This small pilot study tested a drug called BGJ398 in 4 people with a type of bladder cancer that stayed in the bladder lining but came back after standard treatment. The goal was to see if the drug could make the tumor disappear. The study is complete, but results are not yet re…

This study tested whether a device called Nevisense can provide useful information about atypical moles during routine skin cancer screening. Forty adults with many moles (at least 100) and several large moles took part. The goal was to see if the device's measurements could help…

This study tested a new type of PET scan that uses a radioactive tracer called 89Zr-DFO-huJ591 to find prostate cancer that has spread to other parts of the body, especially the bones. 77 men with metastatic prostate cancer received both the experimental scan and standard scans (…

This study tested whether a one-time colonoscopy is better than yearly stool tests for finding early signs of colorectal cancer in healthy people aged 50 to 69. About 5,000 participants were randomly assigned to one of the two screening methods. The goal was to see which approach…

This study tested whether a special gel (Oleogel-S10) helps heal skin burns caused by radiation therapy in breast cancer patients. The gel was used together with a standard steroid cream. The study included 18 adults with stage I-IV breast cancer who developed moderate to severe …

This study tested a special therapy called Managing Anxiety from Cancer (MAC) to see if it helps reduce anxiety in older adults (65+) with cancer and their caregivers. 26 people took part, and the therapy was compared to usual care. The goal was to improve emotional well-being an…

This study tested whether a 30-week walking program is safe for cancer patients who have recovered from COVID-19. Three adults who had been hospitalized for COVID-19 and treated for cancer in the past took part. The goal was to see if the exercise caused few or mild side effects.

This study looked at whether a low-dose vaginal estrogen tablet (Vagifem) is safe for postmenopausal women who have had breast cancer and are taking aromatase inhibitors. The concern is that estrogen absorbed into the blood might raise the risk of cancer coming back. Researchers …

This study looked at 111 people who had surgery for early-stage cervical or vulvar cancer to find out how many develop lower leg swelling (lymphedema). Researchers used a questionnaire to collect information, with no new treatments or tests involved. The goal is to better identif…

This study tested whether a hyperspectral camera can measure blood flow and oxygen levels in the skin of healthy people. Eight volunteers aged 18 to 45 had their arm blood flow measured as blood vessels tightened or relaxed. The goal was to see if the camera works, not to treat a…

This study looked at 133 Hodgkin lymphoma survivors who had chest radiation at least 5 years ago. Researchers compared two heart tests—cardiac MRI and stress echocardiogram—to see which one finds heart damage earlier. The goal is to improve long-term heart monitoring for survivor…