New phone therapy aims to ease anxiety in older cancer patients
NCT ID NCT03168971
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a telephone-based therapy called Managing Anxiety from Cancer (MAC) for older adults (65+) with cancer and their caregivers. The therapy includes seven sessions covering relaxation, communication, and problem-solving skills. The goal was to see if it reduces anxiety better than usual care. Only 26 people took part, so results are preliminary.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Managing Anxiety from Cancer (MAC) therapy (telephone-administered psychological intervention)
- What this could lead to
- If it works, this could provide a practical, home-based therapy to reduce anxiety and improve quality of life for older cancer patients and their caregivers.
- What could go wrong
- This is a very small pilot study with only 26 participants, so results may not apply to everyone. The therapy is still experimental and may not be more effective than usual care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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26 people
The number who actually took part.
- Started
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Jan 2019
- Finished
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Oct 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: PATIENTS: * Age 65 or older * Confirmed diagnosis of breast, lymphoma, genitourinary, thoracic, gynecological or gastrointestinal cancer, currently on active treatment or within six months of completion of treatment * As determined by the patient's primary oncologist and/or study staff, physically and cognitively able to complete study procedures * English fluent (as per self-reported fluency of "very well")\*\* * In the judgment of the investigators and/or consenting professional, able to perform informed consent * Has a primary informal caregiver (as defined by an unpaid individual who provides the patient with emotional, physical, and/or practical support) who is willing and able to participate in the study * As part of the patient-caregiver dyad, at least one member reports elevated anxiety as defined by a score of 8 or greater on the anxiety subscale of the Hospital Anxiety and Depression Scale (HADS) * As per self-report, residency in New York or ability to complete sessions in New York * Able to communicate over the phone for sessions * Willingness to be audio-recorded for assessments and, if applicable, study sessions CAREGIVERS: * Age 21 or older * In the judgment of the investigators and/or consenting professional, able to perform informed consent * As part of the patient-caregiver dyad, at least one member reports elevated anxiety as defined by a score of 8 or greater on the anxiety subscale of the Hospital Anxiety and Depression Scale (HADS) * English fluent (as per self-reported fluency of "very well")\*\* * Is a primary informal caregiver (as defined by an unpaid individual who provides the patient with emotional, physical, and/or practical support) for an MSK patient * As per self-report, residency in New York or ability to complete sessions in New York * Able to communicate over the phone for sessions * Willingness to be audio-recorded for assessments and, if applicable, study sessions Exclusion Criteria: PATIENTS: * Endorsing active suicidal ideation on the item, "In light of your current circumstances, have you ever had thoughts of killing yourself?" * As per oncologist or self-report, too weak or cognitively impaired to participate in the intervention and complete the assessments * Per self-report/screening measures, has received cognitive-behavioral therapy since cancer diagnosis * As per medical record or self-report, currently being treated for schizophrenia, substance use or dependence, and/or bi-polar disorder * Anxiety due solely to a medical procedure as determined by a patient-report item on the screening questionnaire CAREGIVERS: * Endorsing active suicidal ideation on the item, "In light of your current circumstances, have you ever had thoughts of killing yourself?" * Per self-report/screening measures, has received cognitive-behavioral therapy since patient"s cancer diagnosis * As per self-report, currently being treated for schizophrenia, substance use or dependence, and/or bi-polar disorder * If female, currently pregnant
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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