Medsir

This study tests a new three-drug combination (zanidatamab, tucatinib, and chemotherapy) in people with advanced HER2-positive breast cancer that has spread or cannot be removed by surgery. The goal is to find the safest dose and see if the combination shrinks tumors. About 24 ad…

This study tests a new drug called bexmarilimab combined with standard chemotherapy (doxorubicin) for people with metastatic soft-tissue sarcoma, a rare cancer that has spread. The goal is to find the safest dose and see if the combination helps control the disease longer. About …

This study tests special drugs that can both find and treat cancer that has spread to the brain. About 10 adults with advanced breast cancer or other solid tumors will receive a radioactive agent to see if it reaches the brain tumors and helps shrink them. The goal is to measure …

This study tests a new two-drug combination (camizestrant and ribociclib) in 150 people with advanced hormone receptor-positive (HR+) breast cancer. Participants must have had at least 5 years of prior hormone therapy. The goal is to see how long the cancer stays under control be…

This study tests whether giving atropine before chemotherapy can prevent severe diarrhea in people with advanced breast cancer. About 30 participants will receive atropine alongside the drug sacituzumab govitecan. The goal is to make treatment more tolerable by reducing a common …

This study looks at stored tumor samples from 244 people diagnosed with biliary tract cancer in the last 15 years. Researchers will measure five specific biomarkers to see how they relate to patient outcomes. The goal is to better group patients by their cancer type, which could …