Medsir

This study is testing whether adding a new antibody drug called bexmarilimab to a standard chemotherapy (doxorubicin) is safe and more effective for people with metastatic soft-tissue sarcoma. The trial will enroll about 278 adults who have not yet received doxorubicin for their …

This trial is testing a new combination of three drugs as the first treatment for people with advanced triple-negative breast cancer that tests positive for a marker called PD-L1. The goal is to see if the combination is safe and can shrink tumors and control the cancer. It will …

This study is testing whether combining two drugs, camizestrant and ribociclib, can better control advanced hormone-positive breast cancer. It will involve about 150 adults whose cancer has progressed despite at least 5 years of prior hormone-blocking therapy. The main goal is to…

This study is testing a new type of 'theranostic' drug that first acts like a medical dye to locate cancer in the brain and then delivers targeted radiation to treat it. It is for adults with solid tumors, including HER2-positive breast cancer, that have spread to the brain and a…

This study aims to see if giving atropine, a common medication, before chemotherapy can prevent severe diarrhea in patients with advanced breast cancer. It will involve about 30 patients who are receiving a specific chemotherapy drug called sacituzumab govitecan. The main goal is…