Massachusetts General Hospital

This study tests whether repeat doses of the BCG vaccine (traditionally used for tuberculosis) can improve blood sugar control and reduce insulin needs in children aged 8 to 18 with type 1 diabetes. Researchers will monitor changes in HbA1c, blood sugar swings, and insulin use ov…

This study looks for better ways to diagnose allergies to cephalosporin antibiotics, which are commonly used but can cause serious reactions. Researchers will test 300 adults with a history of possible allergic reactions using skin tests and controlled drug challenges. The goal i…

This study tests whether a gentle, non-invasive brain stimulation technique called tACS can reduce chronic low back pain. Researchers will enroll 80 adults aged 18-60 who have had low back pain for at least 6 months. Participants will receive either real tACS or a sham (fake) sti…

This study looks at whether adding a special palliative care program (called PEACE) to usual cancer care can improve quality of life for adults with blood cancers like lymphoma, leukemia, or multiple myeloma who are receiving cell therapy. About 90 participants will be randomly a…

This study looks at how well a special implant (IlluminOss) works for people with pelvic fractures from cancer that has spread or from aging. The goal is to see if it reduces pain and helps patients move better. About 100 adults will be followed for up to 2 years after surgery, r…

This study tests whether a video and a guide (called VIDEO-PEDS) can improve conversations between doctors and parents of children with cancer. It involves 567 parents and children aged 0-12. The goal is to see if the tool helps parents talk about treatment goals, limits on life …