Massachusetts General Hospital

This study tests whether adding high-dose vitamin D3 to standard anti-TNF therapy can improve symptoms and reduce inflammation in people with active Crohn's disease or ulcerative colitis. About 100 adults starting anti-TNF treatment will receive either vitamin D3 or a placebo for…

This study aimed to see if adding two immune-boosting drugs (zimberelimab and domvanalimab) to standard chemotherapy could help people with operable stomach or esophageal cancer. All participants would have received the treatment before and after surgery, then be followed for up …

This study is testing new optical imaging tools that can look at gut tissue samples without destroying them. Researchers want to see if these images can help detect diseases like those affecting the stomach or intestines. About 200 people scheduled for a routine upper endoscopy o…