Mario Negri Institute For Pharmacological Research

This study tested whether adding pioglitazone (a diabetes drug) to trabectedin (a chemotherapy) can help shrink or control liposarcoma, a rare cancer of fat tissue. It included 10 adults whose cancer had stopped growing but not shrunk after at least 4 cycles of trabectedin alone.…

This completed study tested whether programs involving schools and families could help prevent childhood obesity. Researchers worked with 226 children aged 6-11 to promote healthy eating and active lifestyles. The goal was to see if these combined efforts could reduce the risk of…

This study looked at 10 people with a kidney disease called ADPKD to see if a specific gene change (a deletion in the PKD2 gene) is common in families from the Bergamo area. Researchers interviewed participants about their health and family history to understand how this gene cha…

This study looked at blood samples from 48 people with membranous nephropathy, a kidney disease, to see how treatments that deplete B-cells affect specific immune cells linked to the disease. Researchers measured levels of PLA2R-specific B-cells before and after therapy to unders…