Laureate Institute For Brain Research, Inc.

This study tests whether a keto-like supplement can change how the brain responds to positive and negative experiences in people with moderate to severe depression. 75 adults will take either the supplement or a placebo three times daily for 8 weeks, and undergo brain scans and q…

This study tests whether a gentle ultrasound treatment can help calm overactive brain circuits linked to PTSD. Sixty-six frontline healthcare workers with PTSD symptoms will receive either real or fake ultrasound to the brain's cingulate cortex. Researchers will measure changes i…

This study tests whether recalling a positive memory can improve mood and decision-making in 80 adults with methamphetamine use disorder who are in treatment. Participants will do computer tasks and have brain scans before and after recalling a happy memory or a neutral one. The …

This study uses brain scans and machine learning to understand why people with bipolar disorder experience rapid mood swings. Researchers will compare 72 adults with bipolar disorder and healthy controls while they recall memories and practice boosting positive emotions. The goal…

This study looks at 140 people with treatment-resistant depression to see how low-intensity focused ultrasound affects brain circuits linked to mood and thinking. The goal is not to treat depression directly, but to understand which brain connections cause symptoms like loss of p…

This study looks at how the brain reacts to threats in people with depression, anxiety, or both. About 165 adults will take a single dose of an anti-anxiety drug or a placebo and then have their brain activity measured with MRI and eye-blink tests. The goal is to find differences…

This study looks at how sensing your body from the inside (interoception) relates to body image problems in anorexia nervosa. About 102 people with anorexia will try either floatation therapy or watching videos, both with mindfulness training. The goal is to understand these conn…

This study compares how the brain and immune system react to a mild, temporary inflammatory trigger in 90 people with major depression and 90 healthy volunteers. Participants receive either an immune-stimulating substance or a placebo, and researchers measure changes in mood, bra…

This study uses low-intensity focused ultrasound to safely and temporarily change how different parts of the brain communicate in healthy volunteers. Researchers will test different doses to see which has the strongest effect on brain networks linked to mood and anxiety. The goal…