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Sound waves probe the depressed brain: a new way to understand why treatments fail

NCT ID NCT07166289

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 27 times

Summary

This study looks at 140 people with treatment-resistant depression to see how low-intensity focused ultrasound affects brain circuits linked to mood and thinking. The goal is not to treat depression directly, but to understand which brain connections cause symptoms like loss of pleasure and repetitive negative thoughts. By mapping these circuits, researchers hope to find better targets for future therapies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Laureate Institute for Brain Research

    RECRUITING

    Tulsa, Oklahoma, 74136, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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