Laureate Institute For Brain Research, Inc.

This early-stage trial tests whether Floatation-REST — floating in a shallow, soundproof, light-free pool of Epsom salt water — can safely reduce post-traumatic stress symptoms and burnout in frontline healthcare workers and first responders. Fifteen participants will be randomly…

This study tests whether a keto-like supplement, taken as a drink three times daily for 8 weeks, changes brain activity in people with moderate to severe depression. Researchers will use brain scans to compare the supplement to a placebo in 75 adults. The goal is to see if the su…

This study tests whether low-intensity focused ultrasound (LIFU) can calm overactive brain areas linked to PTSD in frontline healthcare workers. Sixty-six participants will receive either real or fake ultrasound to the brain's cingulate cortex. Researchers will measure changes in…

This study looks at how the immune system and brain talk to each other in people with major depression. Researchers will give a harmless substance (LPS) to temporarily activate the immune system and then measure brain activity and mood changes. The goal is to understand the links…

This study uses brain scans (fMRI) to understand why people with bipolar disorder experience unstable moods compared to healthy individuals. Researchers will ask 72 participants to recall personal memories and practice boosting positive feelings while their brain activity is reco…

This study tests whether low-intensity focused ultrasound can temporarily change brain activity in people with treatment-resistant depression. Researchers will scan participants' brains before and after ultrasound to see how it affects mood-related circuits. The goal is not to tr…

This study uses brain imaging and a single dose of the anti-anxiety drug lorazepam to understand how people with both depression and anxiety disorders process threats differently than those with depression alone. About 165 adults will complete two sessions involving startle tests…

This study uses low-intensity focused ultrasound to temporarily change activity in deep brain areas involved in mood and anxiety. Researchers will scan the brains of 66 healthy adults before and after ultrasound to see how it alters communication between key regions. The goal is …

This study explores whether floating in a warm, saltwater tank (floatation-REST) while practicing mindfulness can reduce body image dissatisfaction in people with anorexia nervosa. 102 participants will be randomly assigned to either the floatation therapy or a control group watc…