Scientists trigger immune response to uncover Depression's hidden brain patterns
NCT ID NCT04751331
First seen May 12, 2026 · Last updated May 19, 2026 · Updated 1 time
Summary
This study compares how the brain and immune system react to a mild, temporary inflammatory trigger in 90 people with major depression and 90 healthy volunteers. Participants receive either an immune-stimulating substance or a placebo, and researchers measure changes in mood, brain activity, and blood markers. The goal is to understand why some people with depression have heightened inflammation and how this affects their symptoms, which could lead to more personalized treatments.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Laureate Institute for Brain Research
RECRUITINGTulsa, Oklahoma, 74136, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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