Kyowa Kirin Co., Ltd.

This study tests whether KHK4951 eye drops can safely improve vision in people with wet age-related macular degeneration (nAMD), a leading cause of vision loss. About 180 participants will use the drops or a placebo to see if they reduce fluid buildup and preserve eyesight. The g…

This study tests an experimental drug called ME-401 in 61 Japanese adults whose indolent B-cell non-Hodgkin's lymphoma has returned or stopped responding to at least two prior treatments. The goal is to see if the drug can shrink tumors and how safe it is. Participants must not h…

This study tests whether KHK4951 eye drops can improve vision in people with diabetic macular edema (DME), a condition where fluid builds up in the eye due to diabetes. About 150 adults with DME will use the eye drops daily for several months. The goal is to see if the drops can …

This early-stage study tests a new drug called KK4277 in healthy volunteers and people with lupus (SLE or CLE). The main goal is to check if the drug is safe and tolerable. Researchers will also measure how the drug moves through the body. The study does not aim to cure lupus, bu…

This study follows 226 people with X-linked hypophosphatemia (XLH), a rare genetic bone disease, for up to 10 years. Researchers will measure height, walking ability, and other health factors to better understand how the disease progresses and affects daily life. The goal is to g…

This study follows people with aplastic anemia who previously received the drug romiplostim in earlier clinical trials. The goal is to see how well the treatment works over up to 5 years and to monitor any long-term side effects, such as new chromosome changes or blood cancers. A…