Khyber Medical University Peshawar

This trial tests whether orlistat, a weight-loss medication, can improve hormonal and metabolic features in women with polycystic ovary syndrome (PCOS). Women aged 18-45 with PCOS will receive either orlistat or a placebo, alongside standard lifestyle advice, for three months. Th…

This Phase 3 trial investigates whether a psychedelic drug, psilocybin, combined with a specialized trauma-focused therapy (SIRT), can improve depression and anxiety in people with trauma-related major depressive disorder. The study also looks at changes in gut-brain axis biomark…

Club foot is a common birth defect where a baby's foot is twisted out of shape. The standard treatment uses weekly plaster casts to gradually correct the foot. This study tests whether changing the cast twice a week instead of once works just as well or better. About 144 babies u…

This trial tests whether a community-based learning program can help prevent and control type 2 diabetes in rural Pakistan. Over 12,000 adults aged 20 and older will participate in group sessions focused on healthy behaviors. The study will measure changes in blood sugar levels a…

Diabetes patients often suffer from dry mouth, which affects eating, speaking, and quality of life. This study tests whether endocrinologists can deliver simple oral care—like screening, counseling, and saliva substitutes—during routine diabetes visits. Researchers will follow 80…

This trial tests whether a culturally adapted, nurse-led program called COPE can improve the psychological wellbeing of primary caregivers of children with autism spectrum disorder in Pakistan. The program includes four weekly sessions focused on coping skills, emotional regulati…

This study tests whether certain supplements—prebiotics, probiotics, omega-3s, and vitamin B1—can reduce ADHD symptoms in children aged 6 to 12. Over 12 weeks, 68 kids will receive either a gut-focused supplement, a brain-focused supplement, a combination, or a placebo. Researche…

This study tests whether adding mechanical lumbar traction to a specific spinal mobilization technique (SMWLM) provides better pain relief and function than the mobilization alone for people with lumbar radiculopathy (sciatica). Thirty-two adults with a confirmed disc bulge will …

This study looks at whether chewing gum after gastrointestinal surgery can help the bowels start working again sooner. About 96 adults having open abdominal surgery will either chew gum or not, and researchers will measure how quickly they pass gas and have their first bowel move…

This study follows 832 children from remote farming communities in Pakistan to see how their diet and nutrition affect their growth and development up to age 5. Researchers will measure body mass index, head circumference, and developmental skills using questionnaires. The goal i…