International Aids Vaccine Initiative

This early-stage study tests three experimental mRNA vaccines designed to train the immune system to fight HIV. About 96 healthy adults without HIV in South Africa will receive either the vaccine or a placebo. The main goals are to check safety and see if the vaccines trigger str…

This early-stage trial tests a new HIV vaccine called GRAdHIVNE1 in 120 healthy adults, both with and without HIV, in southern Africa. The main goal is to check if the vaccine is safe and to see how well it triggers the immune system. Participants will receive either the vaccine …

This study tests a new vaccine called MTBVAC to see if it can prevent tuberculosis (TB) in people aged 14 to 45 living in areas where TB is common. About 5500 volunteers will receive either the vaccine or a placebo and be monitored for up to 3 years. The goal is to find a safe an…

This early-stage study tests a new vaccine against Marburg virus, a rare but deadly disease. About 112 healthy adults aged 18-50 will receive either the vaccine or a placebo to check for side effects and measure immune responses. The goal is to see if the vaccine is safe and prom…