International Aids Vaccine Initiative

This early-stage trial tests a new HIV vaccine called GRAdHIVNE1 in 120 healthy adults in southern Africa, including some living with HIV. The vaccine uses a harmless gorilla virus to deliver HIV protein bits to train the immune system. The main goal is to check safety and see if…

This early-stage study tests whether new mRNA-based vaccines for HIV are safe and can trigger an immune response. About 96 healthy adults without HIV in South Africa will receive either the vaccine or a placebo. The goal is to see if the vaccines can train the body to make specia…

This study tests a new vaccine called MTBVAC to see if it can prevent tuberculosis (TB) in people aged 14 to 45 who live in areas where TB is common. About 5,500 volunteers will receive either the vaccine or a placebo, and researchers will monitor them for up to 3 years to check …

This early-stage trial tests a new vaccine designed to protect against Marburg virus disease, a rare but severe illness. About 112 healthy adults aged 18 to 50 will receive either the vaccine or a placebo to check for side effects and measure immune responses. The goal is to see …