International Aids Vaccine Initiative

This early-stage study tests a new vaccine designed to prevent Sudan virus disease, a severe illness similar to Ebola. About 112 healthy adults aged 18-50 will receive either the vaccine or a placebo to check for side effects and measure immune responses. The goal is to see if th…

This early-stage trial tests a new vaccine (rVSVΔG-MARV-GP) to see if it is safe and triggers an immune response against Marburg virus, a rare but severe disease. About 112 healthy adults aged 18-50 will receive either the vaccine or a placebo. The study focuses on side effects a…

This study tests a new vaccine called MTBVAC to see if it can prevent tuberculosis (TB) disease in teens and adults aged 14 to 45 who live in areas where TB is common. About 5,500 volunteers will receive either the vaccine or a placebo, and researchers will track who develops TB …

This Phase 1 trial is testing a new HIV vaccine called GRAdHIVNE1, made using a harmless gorilla virus to deliver HIV protein pieces. The study will enroll 120 healthy adults in southern Africa, some living with HIV and some without, to check safety and measure immune responses. …