Institute Of Cancer Research, United Kingdom

This phase 3 trial is for postmenopausal women with a common type of breast cancer that has a high chance of returning. Participants receive either standard hormone therapy alone or with the addition of abemaciclib, a targeted drug that blocks cancer cell growth. The goal is to s…

This study looks at whether men with advanced prostate cancer that no longer responds to hormone therapy have certain gene changes that make them respond better to the chemotherapy drug carboplatin. Researchers will first test participants for these gene changes, and those with t…

This early-phase trial tests a combination of two experimental drugs, defactinib and VS-6766, in people with advanced solid tumors that have not responded to standard treatments. The study includes patients with certain lung, ovarian, pancreatic, and endometrial cancers. The main…