I.m. Sechenov First Moscow State Medical University
Clinical trials sponsored by I.m. Sechenov First Moscow State Medical University, explained in plain language.
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Ballet Dancers' teeth: new ceramic filling outperforms standard composite
Disease control CompletedThis study tested two dental filling materials in 20 professional ballet dancers with tooth decay or wear near the gum line. One group received a ceramic-like material (PICN) and the other a self-hardening composite. After 24 months, none of the ceramic fillings failed, while 20-…
Phase: NA • Sponsor: I.M. Sechenov First Moscow State Medical University • Aim: Disease control
Last updated May 26, 2026 11:03 UTC
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Gum graft showdown: collagen vs. your own tissue for implant success
Disease control CompletedThis study tested two ways to make the gums thicker around dental implants in 52 adults with thin gum tissue. One method used a small piece of the patient's own connective tissue, while the other used a collagen matrix. The researchers measured how much the gums thickened, pain l…
Phase: NA • Sponsor: I.M. Sechenov First Moscow State Medical University • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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Could a common gout drug ease a tough type of heart failure?
Disease control CompletedThis study tested whether colchicine, an anti-inflammatory drug used for gout, can reduce inflammation in people with a specific type of heart failure called HFpEF. 42 adults with heart failure symptoms and signs of inflammation took colchicine. The goal was to see if the drug lo…
Phase: PHASE1, PHASE2 • Sponsor: I.M. Sechenov First Moscow State Medical University • Aim: Disease control
Last updated May 18, 2026 12:04 UTC
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AI eye exam: new tool spots high blood pressure damage in seconds
Diagnosis CompletedThis study tested an artificial intelligence (AI) tool called RetinAIcheck to see how well it can detect and grade eye damage caused by high blood pressure (hypertensive retinopathy). Researchers used 729 patients' eye photos and compared the AI's results to assessments by eye do…
Sponsor: I.M. Sechenov First Moscow State Medical University • Aim: Diagnosis
Last updated May 26, 2026 11:04 UTC
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Sleep app study shows promise for chronic insomnia
Symptom relief CompletedThis study tested an online program (iCBT-I) to help people with chronic insomnia sleep better. 107 adults with chronic insomnia used the program alongside their usual care. Researchers measured changes in sleep quality and how much the program cost.
Phase: NA • Sponsor: I.M. Sechenov First Moscow State Medical University • Aim: Symptom relief
Last updated May 26, 2026 11:01 UTC
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Throat gas study aims to boost oxygen therapy for COVID-19 patients
Knowledge-focused CompletedThis study looked at how different oxygen delivery methods affect oxygen and carbon dioxide levels in the throat of 14 healthy volunteers. The goal was to understand why high-flow oxygen therapy works better for some COVID-19 patients. The findings could help improve oxygen treat…
Phase: NA • Sponsor: I.M. Sechenov First Moscow State Medical University • Aim: Knowledge-focused
Last updated May 26, 2026 10:55 UTC
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Gut inflammation linked to hardened arteries in new study
Knowledge-focused CompletedThis study looked at whether people with inflammatory bowel disease (IBD) have a higher risk of developing atherosclerosis, a condition where arteries harden and narrow. Researchers measured artery stiffness and thickness in 115 adults with IBD. The goal was to understand the con…
Sponsor: I.M. Sechenov First Moscow State Medical University • Aim: Knowledge-focused
Last updated May 22, 2026 14:03 UTC