Helsinki University Central Hospital

This study looked at the long-term effects of oral immunotherapy (OIT) for children with severe milk allergy. Researchers wanted to see if OIT helps children drink more milk over time and improves their quality of life. They also studied the cost of the treatment. The study inclu…

This study tested a monthly injection of mepolizumab (100 mg) versus placebo in 95 adults with severe asthma, nasal polyps, and aspirin sensitivity. The goal was to see if the drug could improve sinus symptoms, shrink nasal polyps, and reduce the need for other medications. Resul…

This study looked at whether offering families extra help from a pediatrician and social worker after a child's dental surgery under anesthesia can improve follow-up care. 89 children with severe tooth decay participated. The goal was to see if this support leads to fewer missed …

This study looked at two methods to treat a condition called concha bullosa, where the middle turbinate inside the nose is swollen and blocks airflow. 62 adults with chronic sinusitis were randomly assigned to have the swollen part either crushed or surgically removed during stan…

This study looked at how grapefruit juice and a drug called cobicistat affect the amount of esketamine in the blood. Esketamine is used for depression and pain relief. Twelve healthy adults took esketamine as a nasal spray or by mouth, with either grapefruit juice, cobicistat, or…

This study looked at how carvedilol (a heart drug) and diclofenac (a painkiller) change the way the liver processes other medications. Twelve healthy adults took a mix of test drugs with either carvedilol, diclofenac, or a placebo. The goal was to see if these common drugs cause …