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Grapefruit juice tested for impact on depression drug

NCT ID NCT06726382

Summary

This study examined how grapefruit juice and another medication affect how the body absorbs esketamine, a drug used for depression and pain. Researchers gave 12 healthy volunteers esketamine either as a nasal spray or by mouth, along with either grapefruit juice, the medication cobicistat, or water. They measured drug levels in the blood over 24 hours to understand these interactions better.

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Contacts and locations

Locations

  • Department of Clinical Pharmacology

    Helsinki, Finland

Conditions

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