Hadassah Medical Organization

This study tests a new treatment for people with advanced cancers that have spread and express a protein called NY-ESO-1. Patients receive a single infusion of their own immune cells that have been genetically modified to recognize and attack cancer cells. The goal is to see if t…

This study looks at whether eating fewer carbohydrates (up to 120 grams per day) can help pregnant women with diabetes who need insulin achieve better blood sugar control compared to the standard high-carb diet. The researchers will monitor blood sugar levels and pregnancy outcom…

This early-stage study tests a new treatment called HBI0101 CART for people with multiple myeloma, a type of blood cancer, that has returned or not responded to standard therapies. The treatment uses a patient's own immune cells, modified in a lab to better recognize and kill can…

This study tests whether a single dose of zoledronic acid can prevent the bone loss that often happens when people start HIV medication. About 110 adults newly diagnosed with HIV will either receive the drug or just be monitored. Researchers will track bone density over four year…

This study tests a personalized cancer vaccine made from patients' own tumor cells. The goal is to train the immune system to fight metastatic cancers like melanoma, breast, lung, and colorectal cancer. Participants receive eight injections over 16 weeks. The study is for adults …

This study tests whether watching relaxing virtual reality (VR) scenes before egg retrieval can reduce pain in women freezing their eggs. One hundred women will be randomly assigned to either standard care or standard care plus a VR relaxation session. Pain levels are measured be…

This study tests a 6-week remote group program called CRAFT-G for breast cancer survivors who have memory and thinking problems after treatment. About 48 women will join online sessions and use a brain-training app. The goal is to see if the program improves mental clarity, mood,…

This study tests whether a cannabis extract containing THC and CBD can reduce sudden nerve-related back pain and the need for strong painkillers. About 200 adults with acute radicular pain will receive either cannabis oil or a placebo, and researchers will track their pain levels…

This early-stage study is testing whether a combination of psilocybin (the active ingredient in magic mushrooms) and D-serine (an amino acid) is safe and how it affects the mind. Ten healthy adults aged 25-60 will receive one of two dose levels. The goal is to see if D-serine can…

This study looks at how genetic differences affect the way healthy adults process the blood thinner warfarin. Researchers will give participants single doses of warfarin and other drugs to measure metabolism and compare it to their DNA. The goal is to better understand why warfar…