Hadassah Medical Organization

This early-stage trial is testing a new treatment called HBI0101 CAR-T for people with multiple myeloma that has come back or stopped responding to standard treatments. The therapy uses a patient's own immune cells, which are modified in a lab to better recognize and attack cance…

This study is for people who had melanoma and, after surgery, are cancer-free or have very little cancer left but face a high risk of it coming back. The treatment is a vaccine made from a specially engineered melanoma cell line that helps the immune system recognize and attack a…

This early-phase trial tests a personalized cancer vaccine made from a patient's own tumor cells or donor cells. The vaccine is designed to teach the immune system to recognize and attack cancer. Up to 50 adults with metastatic melanoma, breast, ovarian, colorectal, gastric, lung…

This early-phase study tests a personalized cell therapy for people with several types of advanced cancer that have spread and express a protein called NY-ESO-1. Participants receive a single infusion of their own immune cells that have been genetically modified to recognize and …

This study looks at whether a moderate carbohydrate diet (up to 120g per day) can help pregnant women with diabetes who need insulin achieve better blood sugar control compared to the standard high-carb diet. The trial will include 120 pregnant women and track their glucose level…

This study tests whether a single intravenous dose of zoledronic acid can prevent the bone loss that often happens when people start HIV medications. Researchers will compare bone density changes over 48 months in 110 newly diagnosed HIV patients who either receive the drug or ju…

This study tests a remote group program called CRAFT-G for breast cancer survivors who struggle with memory, focus, and thinking after treatment. The program includes six online group sessions led by an occupational therapist, plus brain-training exercises done at home. Researche…

This study tests whether a cannabis oil containing THC and CBD can reduce sudden, sharp back pain from a pinched nerve and lower the need for strong painkillers. About 200 adults with severe pain lasting less than 12 weeks will receive either cannabis oil or a placebo, and their …

This study tests if watching relaxing virtual reality (VR) scenes before an egg retrieval procedure can lower pain. One hundred women having elective egg freezing will either get standard care or standard care plus a VR relaxation session. Pain levels are measured with a simple 0…

This study looks at how genetic differences in the CYP2C9 enzyme affect the way healthy volunteers process warfarin and similar drugs. Researchers will give participants single doses of one or more of these drugs and measure how their bodies break them down. The goal is to better…

This study tests whether a real-time artificial intelligence (AI) dashboard can help doctors make better decisions during labor for first-time mothers. About 400 women will be randomly assigned to either standard care or care with the AI tool visible in their medical records. The…

This early-stage study is testing whether adding D-serine to psilocybin (the active ingredient in magic mushrooms) can reduce its psychedelic effects while keeping it safe. Ten healthy adults aged 25-60 will receive one of two dose combinations and be closely monitored for side e…