Hackensack Meridian Health

This early-phase study tests a combination of three drugs (ibrutinib, lenalidomide, and rituximab) in people with mantle cell lymphoma that has returned or not responded to prior treatment. The main goal is to find the safest dose of this combination by monitoring side effects. U…

This study tests a combination of four drugs—carfilzomib, lenalidomide, vorinostat, and dexamethasone—in people with multiple myeloma that has relapsed or not responded to prior treatment. The goal is to find a safe dose and see if the combination helps control the cancer. Sevent…

This study tests a combination of three drugs—carfilzomib, iberdomide, and dexamethasone—in people newly diagnosed with multiple myeloma who are eligible for a stem cell transplant. The goal is to see if this mix is safe and effective at shrinking the cancer before transplant. Ab…

This study aimed to test whether giving the antibiotic ceftriaxone every 5 days for about 6 weeks could kill the bacteria causing persistent Lyme disease symptoms. It planned to enroll people aged 18-75 with Post-Treatment Lyme Disease Syndrome. However, the trial was withdrawn b…

Researchers are studying whether a blood test can detect prostate cancer by finding prostasomes, tiny particles that prostate cancer cells release into the blood. The trial enrolls men with elevated PSA levels or diagnosed prostate cancer who have not yet received treatment. The …

This study was designed to see if measuring blood flow resistance in tiny leg vessels could predict whether a limb could be saved after artery-opening procedures in people with critical limb ischemia. It planned to enroll patients with severe leg artery disease and use a special …

This study investigates whether keeping a headache diary helps adults with migraine feel better and manage their condition. Participants track their headaches in a virtual diary, and researchers measure changes in quality of life and disability. The goal is to see if this low-cos…

This study tests whether placing a cryopreserved umbilical cord allograft around nerves during robotic prostatectomy helps men regain erectile function and bladder control sooner. About 100 men with prostate cancer will be randomly assigned to receive either standard surgery or s…

This pilot study looks at whether full-term newborns with mild breathing problems can safely transition without a breathing tube called CPAP. Researchers will observe 22 babies born via scheduled C-section who show mild signs like flaring nostrils or light grunting. Half will rec…

This study explores how to add a mental health program called Mothers and Babies into existing home visiting services for pregnant people and new parents in Iowa and Indiana. Researchers will work with 1,750 home visitors and program recipients to see how well the program is adop…