Guangdong Provincial People's Hospital

This study tests whether adding two immune-boosting drugs (PCSK9 and PD-1 inhibitors) to standard chemoradiation can help shrink tumors in people with a specific type of advanced rectal cancer. About 30 adults aged 18-75 with no distant spread are taking part. The goal is to see …

This study tests whether adding the drug serplulimab to standard chemotherapy (FLOT) can help more patients with stage III stomach cancer achieve a complete response before surgery. About 138 participants will receive either the combination or chemo alone, followed by surgery and…

This study tests a two-step treatment for people with a specific type of lung cancer (EGFR-mutant, stages II to IIIB). First, patients take a targeted pill (almonertinib), then receive a combination of immunotherapy (adebrelimab) and chemotherapy. After these treatments, surgery …

This study tests whether the targeted drug lorlatinib can shrink tumors in people with stage III non-small cell lung cancer that has a specific gene change (ALK fusion). About 48 adults will take lorlatinib before possibly having surgery. The main goal is to see if the cancer com…

This study looks at whether adding venetoclax to standard chemotherapy (HMAs) works better than chemotherapy alone for people newly diagnosed with higher-risk myelodysplastic syndromes (MDS) or chronic myelomonocytic leukemia (CMML). About 224 adults will be observed to see how m…

This study tests whether a drug called crisugabalin can safely reduce pain in people with Parkinson's disease. About 166 adults will take either the drug or a placebo for 12 weeks, and researchers will track their pain levels and any side effects. The goal is to find a better way…

This study tests whether N-acetylcysteine (NAC), a common supplement, can help people with obsessive-compulsive disorder (OCD) that hasn't improved with standard treatments. Researchers will measure brain chemical changes using special scans and check if symptoms get better. The …

This study follows 330 people with non-small cell lung cancer who receive immunotherapy before surgery. Researchers measure cortisol levels at different times to see if changes in this stress hormone relate to how well the tumor responds to treatment. The goal is to find a simple…

This study watches 200,000 Chinese adults with heart disease to see how well their heart and lungs work during exercise. Researchers use a special bike test to measure oxygen use and breathing. They will follow participants for 5 years to see if these tests can predict heart atta…

This study uses artificial intelligence to analyze electrocardiogram (ECG) images and predict if someone will have a heart attack. Researchers will look at past ECGs from 150,000 patients to see if the AI can spot warning signs that doctors might miss. The goal is to develop a to…