Fundación Epic

This study tests a new, very thin stent coated with a drug (sirolimus) in 500 heart disease patients who also take blood thinners. These patients have a high risk of bleeding when they need a stent. The new stent may allow for a shorter course of antiplatelet drugs, potentially r…

This study compares two types of replacement heart valves (Allegra and Sapien) in 104 people whose surgically implanted aortic valve has stopped working properly. The goal is to see which valve does a better job at improving blood flow through the heart. Participants will be rand…

This study is checking if a medical device called Essential Pro is safe and works as intended for people with narrowed or blocked heart arteries. About 100 patients who already received the device as part of their routine care will be followed. Researchers will track heart-relate…

This study is checking how safe and effective the SUPRAFLEX CRUZ stent is for people with blocked heart arteries. About 508 adults who already got the stent as part of their routine care will be followed for a year. Researchers will track serious heart problems like heart attacks…

This study is testing a long stent (a small mesh tube) to treat long blockages in the heart's arteries. The goal is to see if using one long stent is safe and works well for these difficult blockages. About 1,039 adults with coronary artery disease will take part. The main focus …

This study is a registry that will follow about 960 people with coronary artery disease who are treated with the SELUTION sirolimus-eluting balloon, a device that delivers medication to open blocked heart arteries. The goal is to see how safe and effective the balloon is in real-…

This study looks at using a paclitaxel-coated balloon to open up small heart arteries in people with coronary artery disease who also have a high risk of bleeding. The goal is to see if this treatment works well and allows patients to safely stop taking blood thinners after just …

This study compares two types of drug-coated stents (small mesh tubes placed in heart arteries) in 2,100 people who have had a heart attack or unstable chest pain. The goal is to see which stent better prevents heart-related death, heart attacks, or the need for repeat procedures…

This study tests whether using a special device (orbital atherectomy) to grind down calcium deposits before placing a stent is better than the standard balloon method. About 200 adults with hardened heart arteries will be randomly assigned to one of the two approaches. The goal i…

This study looks at two treatments for coronary artery disease in large blood vessels (≥3.5 mm): a drug-coated balloon and a drug-eluting stent. About 94 adults with heart disease will be randomly assigned to one treatment. The main goal is to see how well the treated artery can …

This study compares two imaging methods for guiding treatment of hardened coronary arteries. About 700 adults with heart disease will either receive CT-guided or standard ultrasound-guided care during stent placement. The goal is to see if the CT approach improves stent expansion…

This study looks at 600 people who had a major heart attack and have other blockages that are not severe enough to need immediate treatment. Some of these blockages are unstable and could cause another heart attack. The trial compares two approaches: placing stents in these unsta…

This study follows over 2,000 patients with coronary artery disease who received a device called Sequent Please Neo during routine care. Researchers want to confirm the device is safe and works well by tracking major heart problems like heart attacks or the need for repeat proced…

This study is checking how well a new drug-coated heart stent (Coroflex ISAR NEO) works and how safe it is in 3,000 people with narrowed heart arteries. Participants get the stent as part of their regular care, and doctors will track heart-related events like heart attacks or the…

This study looks at a new method to check blood flow in heart arteries after treatment in patients with blockages in multiple vessels. The new method uses a special wire and a drug (nitroglycerin) instead of the standard drug adenosine, which can cause side effects. Researchers w…

This study looks at how calcium buildup in artery walls affects the healing of a heart stent after one month. Researchers will use a special camera to compare stent struts over calcium deposits to those without calcium. The goal is to understand if calcium slows down the covering…