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Heart valve showdown: which replacement works best?

NCT ID NCT06049654

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 27 times

Summary

This study compares two types of replacement heart valves (Allegra and Sapien) in 104 people whose surgically implanted aortic valve has stopped working properly. The goal is to see which valve does a better job at improving blood flow through the heart. Participants will be randomly assigned to receive one of the two valves.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Freeman Hospital

    RECRUITING

    Newcastle, United Kingdom

  • Hospital Clinico San Carlos

    RECRUITING

    Madrid, 28040, Spain

  • Hospital Clínico Universitario de Salamanca

    RECRUITING

    Salamanca, 37007, Spain

  • Hospital Universitari I Politècnic de La Fe

    RECRUITING

    Valencia, 46026, Spain

  • Hospital Universitari de Bellvitge

    RECRUITING

    L'Hospitalet de Llobregat, 08907, Spain

  • Hospital Universitario Puerta De Hierro

    RECRUITING

    Majadahonda, 28222, Spain

  • Hospital Universitario de La Paz

    RECRUITING

    Madrid, 28046, Spain

  • Manchester University NHS Foundation Trust

    RECRUITING

    Manchester, United Kingdom

  • Morriston Hospital, Swansea

    RECRUITING

    Swansea, United Kingdom

Conditions

Explore the condition pages connected to this study.