Federico Ii University

This study tests whether the drug ranolazine can protect the tiny blood vessels in the heart after a heart attack. One hundred adults who had a major heart attack and have at least one other blocked artery will receive either ranolazine plus standard care or standard care alone. …

This registry is tracking 1,500 Italian patients who are prescribed alirocumab 300 mg injections for high cholesterol. Researchers want to see how consistently patients take the medication and how well it lowers their cholesterol in real-life settings. The study also monitors sid…

This study will follow 3,000 adults in Italy who are already taking Inclisiran, a long-acting injection for high cholesterol. Researchers want to see how consistently patients take the medication and how much it lowers their LDL ("bad") cholesterol in everyday practice. The goal …

This phase 4 trial tests whether adding semaglutide to standard diabetes treatment reduces inflammation and improves blood vessel health in 80 people with type 2 diabetes who have no heart disease. Participants receive either semaglutide injections plus standard care or standard …

This study tests whether a once-daily dual-release hydrocortisone pill (Plenadren) works better than standard multiple-dose glucocorticoids for adults with congenital adrenal hyperplasia. The trial will enroll 150 adults and measure changes in cholesterol, blood sugar, weight, bl…

This study follows children aged 0 to 14 with suspected non-IgE food allergies, which cause digestive symptoms like reflux, colic, or constipation rather than immediate allergic reactions. Researchers will track symptoms, triggers, and growth over time, and analyze blood samples …

This study looks at children with functional gut disorders, like stomach pain or irritable bowel syndrome, to see how many are also allergic to nickel or certain plant proteins called LTPs. Researchers will test for these allergies and also check in the lab whether a supplement c…

This study asks whether compounds in ultra-processed foods, like advanced glycation end-products, might play a role in eosinophilic esophagitis, a chronic inflammatory condition of the esophagus. Researchers will compare the diets of 100 people with and without the disease, using…

This observational study looks at whether taking raw cornstarch with meals helps control blood sugar in adults with glycogen storage disease type I (GSD I). Eight participants will wear continuous glucose monitors and keep food diaries for two weeks. Researchers will compare bloo…

This study is observing 3000 adults with type 2 diabetes in Italy to see how well their heart risks are managed according to current guidelines. Researchers will check if patients are getting the right medications and care. No new treatments are being tested.

This study will follow 1,500 Italian adults taking bempedoic acid for high cholesterol to see how consistently they take the medication and how well it lowers their cholesterol. Researchers will also check for side effects. The goal is to understand real-world use, not to test a …

This study is following 5,000 Italian patients who are taking PCSK9 inhibitor injections (Repatha or Praluent) for high cholesterol. Researchers want to see how consistently patients take their medication and how well it lowers their LDL cholesterol in real life, not just in a la…

This study looks at whether a special green dye (indocyanine green) can help surgeons see and fix leaks during laparoscopic Heller-Dor surgery for achalasia, a condition that makes swallowing difficult. About 70 adults with type I or II achalasia will take part. The dye is inject…

This observational study is looking at how diet, gut bacteria, and genetics influence blood sugar spikes after meals in people with type 1 diabetes. Researchers will track 200 participants using continuous glucose monitors, food diaries, and stool samples. The goal is to find pat…