Federico Ii University

This study compares a new once-daily dual-release hydrocortisone to standard glucocorticoid therapy in 150 adults with congenital adrenal hyperplasia. The goal is to see if the new pill improves cholesterol, blood sugar, weight, blood pressure, and quality of life. Participants m…

This study looks at whether adding semaglutide to standard diabetes care can reduce inflammation and improve blood vessel function in people with type 2 diabetes who have a high risk of heart problems but no major heart disease yet. About 80 adults will be randomly assigned to re…

This study tests whether the drug ranolazine can protect the tiny blood vessels in the heart after a major heart attack. Researchers will enroll 100 adults who have had a specific type of heart attack (STEMI) and have blockages in multiple arteries. Participants will either recei…

This study will follow 3,000 Italian adults who are already taking inclisiran, a medication for high cholesterol. Researchers want to see how consistently patients take the drug and how much it lowers their LDL (bad) cholesterol in everyday practice. The goal is to understand rea…

This study tests whether eating a Mediterranean diet during pregnancy can help prevent allergies in babies. Researchers will enroll 276 healthy pregnant women who are at risk of having a child with allergies. The goal is to see if this diet reduces the chance of allergic diseases…

This study tests whether a common probiotic, Lactobacillus rhamnosus GG (LGG), can reduce stomach issues like constipation and diarrhea in children with autism spectrum disorder (ASD). About 50 children aged 4 to 12 with both ASD and ongoing stomach problems will receive the prob…

This study is a registry that collects information from 3000 adults with type 2 diabetes who visit heart or internal medicine clinics in Italy. The goal is to see how well doctors follow current guidelines for managing heart disease risk. No new treatments are given; it simply ob…

This study looks at whether a special green dye, called indocyanine green, can help surgeons see and fix small leaks in the esophagus during a procedure for achalasia (a swallowing disorder). About 70 adults with type I or II achalasia will be watched during and after surgery. Th…

This study looks at how food, gut bacteria, and genetics work together to affect blood sugar after meals in people with type 1 diabetes. Researchers will track 200 participants' meals, sleep, and blood sugar using a continuous glucose monitor. No treatment is given; the goal is t…

This study is a registry that will observe 1,500 Italian adults already taking alirocumab 300 mg for high cholesterol. Researchers want to see how consistently patients take the medication, how long they stay on it, and how much their LDL (bad) cholesterol drops. It also tracks s…

This study looks at how consistently Italian patients take their PCSK9 inhibitor injections for high cholesterol and how well the treatment works in everyday life. Researchers will track 5,000 adults aged 18-80 who are already prescribed these drugs, measuring adherence, treatmen…

This study looks at how consistently Italian patients take bempedoic acid for high cholesterol and how well it works in everyday life. Researchers will track 1,500 adults aged 18-80 who are already prescribed the drug, measuring adherence, persistence, and LDL cholesterol changes…