Chu De Quebec-universite Laval

This study looks at multiple myeloma patients who are receiving a type of immunotherapy called a BCMA-directed T cell engager. These treatments can weaken the immune system and raise the risk of serious infections. The trial will compare two levels of immunoglobulin (antibody) su…

This study compares two radiation therapy schedules for men with localized prostate cancer. One uses fewer, stronger doses (ultra-hypofractionated) and the other uses slightly more, moderate doses. Both are combined with a brachytherapy boost. The goal is to see which approach ca…

This study compares two types of radiation therapy for men with low- or intermediate-risk prostate cancer: SBRT (a precise, high-dose external beam treatment) and LDR brachytherapy (implanting tiny radioactive seeds). The goal is to see which causes fewer urinary and bowel side e…

This study tests whether adding the drug bicalutamide to standard BCG therapy can lower the chance of bladder cancer returning. About 160 men with non-muscle invasive bladder cancer will be randomly assigned to receive either BCG alone or BCG plus bicalutamide. The goal is to see…

This early-stage trial tests a new skin graft made from a patient's own cells, genetically modified to produce a missing protein that helps skin stay attached. The graft is designed to be permanent and aims to heal wounds in people with recessive dystrophic epidermolysis bullosa …

This study compares a nerve block (paravertebral block) to standard pain medication in 60 women having a mastectomy with immediate breast reconstruction. The goal is to see if the nerve block reduces pain right after surgery and may help prevent long-term chronic pain. Participan…

This study tests if a special online group therapy program can help women with BRCA1/2 gene mutations who have had breast or ovarian cancer feel less afraid of the cancer returning. About 250 women will take part in 11 weekly online sessions. Researchers will compare those who st…

This study aims to see if a self-administered questionnaire can accurately capture family history of rare genetic bone diseases in adults with osteoporosis. Researchers will compare the questionnaire answers to detailed family trees (pedigrees) from 58 participants. The goal is t…

This study looks at whether a quick, painless test called capillaroscopy (examining tiny blood vessels at the base of the fingernail) can help doctors diagnose specific connective tissue diseases sooner in people with undifferentiated connective tissue disease (UCTD). About 40 ad…