Fingertip camera could speed up diagnosis of hidden autoimmune diseases
NCT ID NCT06399822
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a quick, painless test called capillaroscopy (examining tiny blood vessels at the fingernails) can help doctors diagnose specific connective tissue diseases sooner in people with an unclear autoimmune condition. About 40 adults with undifferentiated connective tissue disease (UCTD) will be randomly assigned to get capillaroscopy or usual care. The goal is to see if the test leads to a clearer diagnosis within six months.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2024
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Be aged 18 and over; * Have been diagnosed with undifferentiated connective tissue disease by a rheumatologist; * Meet the preliminary classification criteria for undifferentiated connective tissue disease: present signs and symptoms suggestive of connective tissue disease, but do not meet the criteria for a connective tissue disease and have a positive antinuclear antibody on at least 2 occasions; * Have developed the first signs and symptoms of the disease less than 10 years before recruitment. Exclusion Criteria: * In the opinion of the clinician, have a health condition that does not allow a delay of six months before carrying out the capillaroscopy; * Have been diagnosed and/or meet the classification criteria for another connective tissue disease (for example, systemic lupus, etc.); * Have already performed a capillaroscopy in the past, regardless of the time or the reason; * Be unable to consent or respond to questionnaires.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CHU de Quebec-Université Laval
RECRUITINGQuébec, Quebec, G1V4G2, Canada
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