Children's Hospital Of Fudan University

This study looks at whether atorvastatin, a common cholesterol medicine, is safe and helpful for children with Kawasaki disease who also have heart artery issues. Researchers will check for side effects and see if the drug reduces inflammation. The study involves 9 children in Ch…

This early-stage study tests a new cell therapy called YTS109 in 12 children aged 5 to 17 with severe autoimmune diseases like lupus and scleroderma that haven't responded to standard treatments. The therapy is given as a single IV infusion, and the main goals are to check its sa…

This early-stage study tests a one-time treatment called CS-206 for people aged 12 to 18 with severe sickle cell disease. The therapy uses gene editing to modify the patient's own blood stem cells, aiming to reduce painful crises and hospital stays. Only 5 participants will be en…

This early study tests the safety and effectiveness of the drug decitabine in 6 boys (ages 1 month to 18 years) with XMEN disease, a rare genetic condition that weakens the immune system and causes liver problems. The treatment aims to improve liver function and immune cell activ…

This study compares different blood purification techniques in 120 children with sepsis (a severe infection causing organ damage). The goal is to see which method best removes harmful inflammatory substances from the blood. Researchers will measure changes in inflammation and org…

This study tests whether adding a traditional Chinese medicine (Sanghe Jianghuo Granules) to standard care can better control early puberty in girls aged 5-9 who are also overweight. The goal is to slow down breast development and bone aging, and improve final height. Participant…

This study tests a special nutrition plan for very premature babies (born before 32 weeks or weighing under 3.3 pounds). The plan includes personalized breast milk feeding, early zinc supplements, and routine carnitine. Researchers want to see if this helps babies grow better and…

This study will test a machine-assisted system that uses five simple social games to help identify autism in toddlers aged 1.5 to 2.5 years. Researchers will compare the system's results with standard clinical diagnoses in 1,000 children across China. The goal is to see if this t…

This study looks at whether child life services—special support to help children cope with medical procedures—can make skin prick testing for allergies less painful and less scary. About 140 children aged 1 to 18 will either get this extra support or standard care. Researchers wi…

This pilot study tests a child-friendly breathing exercise program for 30 children aged 6-18 recovering from severe pneumonia. The program is designed to be fun and engaging, and researchers want to see if it helps kids recover faster and makes caregivers happier. Participants wi…

This study will follow 1,000 children admitted to the pediatric intensive care unit (PICU) to see how better antibiotic prescribing affects their survival and how long they stay in the hospital. The goal is to learn which strategies help doctors use antibiotics more wisely, reduc…

This study looks at whether a new set of guidelines for tube feeding can improve care for critically ill children in intensive care. Researchers will train nurses in multiple hospitals to follow these guidelines and then check if they are being used correctly and if children get …

This study aims to see if a new genetic test (mNGS) can quickly and accurately identify the germs causing pneumonia in children on breathing machines. Researchers will compare this test to standard methods in 400 children. The goal is to improve early diagnosis and treatment of t…