Cancer Trials Ireland

This study tested a combination of two drugs—copanlisib and trastuzumab—in 26 women with advanced HER2-positive breast cancer that had worsened after prior treatments. The goal was to find the safest dose and see if the combo could shrink tumors or slow the disease. While not a c…

This study tested whether combining two drugs, Radium-223 and enzalutamide, is safe for men with advanced prostate cancer that has spread to other parts of the body and no longer responds to standard hormone therapy. 45 men participated. The goal was to see how many experienced s…

This study looked at how a special tumor test, called the 21 gene Recurrence Score (OncotypeDx), affects whether doctors recommend chemotherapy for women with a common type of early-stage breast cancer. Researchers tracked 87 patients in Ireland to see if the test results changed…

This study looked at 76 adults with advanced colorectal cancer that has a specific gene change (mutant K-ras). The goal was to find biological markers that can predict how well a combination of chemotherapy (FOLFOX) and the drug bevacizumab works. Researchers measured tumor respo…