Brown University

This phase 2 trial is testing a combination of three drugs (polatuzumab vedotin, glofitamab, and tafasitamab) as a first-line treatment for people with diffuse large B-cell lymphoma or high-grade B-cell lymphoma. The goal is to see if this chemo-free approach can shrink tumors an…

This study tests a new approach called photoimmunotherapy for people with locally advanced or borderline resectable pancreatic cancer. Patients receive an injection of ASP-1929, a drug that attaches to cancer cells and becomes active when exposed to a specific light. During surge…

This study tests a fall prevention program called AL-STEADI in seven assisted living communities. About 700 residents who are at risk of falling will either receive the program or usual care. The goal is to see if the program reduces the number of falls over one year.

This trial tests a suicide prevention program called 'Hand in Hand, We Rise' in six rural Chinese junior high schools. The program combines a strengths-based curriculum for students, gatekeeper training for teachers, and mental health information for caregivers. Researchers are e…

Researchers at Brown University are running a Phase I study to see whether psilocybin changes how healthy adults update their beliefs and form insights. Up to 24 volunteers receive one 25 mg oral dose of psilocybin or an inactive placebo, then complete computer-based tasks that m…

This study tests whether giving breastfeeding mothers a daily iodine-containing multivitamin for 6 months helps their babies' brains and thyroid health. Researchers will compare babies' brain activity and development between moms who get the supplement and those who receive stand…