British Columbia Cancer Agency

This study aims to improve treatment for vulvar cancer by personalizing surgery based on the tumor's characteristics. Researchers will test whether adjusting surgical margins based on whether the cancer is linked to HPV infection or a p53 mutation leads to better outcomes and few…

This study is testing a precise, high-dose radiation treatment for men whose prostate cancer has come back after previous radiation therapy. Doctors use advanced imaging to find the exact spot of the returning cancer and deliver a strong, focused radiation dose directly to that a…

This is a first-in-human study testing a new personalized cell therapy called CLIC-2201 for adults and children with B-cell blood cancers that have returned or not responded to other treatments. The therapy involves collecting a patient's own immune cells, genetically modifying t…

This study is testing whether a cancer drug called atezolizumab works better when given to people whose tumor DNA analysis suggests they might respond to it. It will enroll about 200 adults with various advanced, incurable solid tumors. Participants will receive the drug every th…

This study is testing if shorter, more intense radiation treatments are as well-tolerated and effective as the standard, longer course for men with prostate cancer that has spread to a few other spots in the body. It will compare different radiation methods, focusing on side effe…

This study aims to see if quickly analyzing the genetic makeup of a pancreatic tumor can help doctors choose the most effective treatment. It will enroll 200 adults with pancreatic cancer that has not spread to distant organs. Participants will receive standard chemotherapy and p…

This study aims to find out if a very short course of radiation (2 treatments) is as good as the standard short course (5 treatments) for men with intermediate-risk prostate cancer. Researchers will compare side effects, quality of life, and cancer control between the two schedul…

This study aims to see if a more precise, high-dose form of radiation (SABR) is better than standard palliative radiation at controlling cancer when it has spread to only a few new spots. About 194 adults with solid cancers that have progressed in up to five locations will be ran…

This study is testing whether closely monitoring and managing blood sugar levels might help people with pancreatic cancer respond better to chemotherapy. About 50 participants will use continuous glucose monitors while receiving standard chemotherapy. Half will aim for tight bloo…

This study aims to gather real-world information on how cancer patients feel and how long they live when receiving promising new treatments where the exact benefits and costs are still unclear. It will follow 100 patients, tracking their health outcomes and quality of life throug…

This study aims to understand exactly how a precise, high-dose radiation treatment works for early-stage prostate cancer. Researchers will observe 100 men receiving this treatment, analyzing changes in their blood, tumor tissue, and gut bacteria before and after. The goal is to l…

This study aims to improve treatment for people with advanced or metastatic cancer by analyzing the unique genetic makeup of their tumor. Researchers will sequence the DNA and RNA from a patient's tumor and blood sample to identify genetic 'drivers' of the cancer. The goal is to …

This study aims to understand advanced pancreatic cancer better by analyzing the genetic makeup of patients' tumors. Researchers will collect tumor samples and blood from about 190 patients starting chemotherapy to look for patterns in their genes. The goal is to see if these gen…

This study aims to collect real-world information on how patients with rare cancers or rare genetic changes in their cancer fare when using approved targeted therapies. It will track survival, quality of life, and how well the treatment works. The goal is to gather strong evidenc…