British Columbia Cancer Agency

This study tests a high-dose-rate brachytherapy (internal radiation) for men whose prostate cancer has returned after previous external beam radiation. About 30 participants will receive a targeted radiation implant to the area of recurrence, aiming to control the cancer while li…

This study tests if shorter, more intense radiation (SABR or brachytherapy) is as safe and effective as standard radiation for men with prostate cancer that has spread to a few other places in the body. About 168 participants will receive one of the radiation types alongside long…

This study tests a drug called atezolizumab in about 200 adults with advanced solid tumors (like breast, lung, or colon cancer) whose tumor DNA suggests the drug might help. Participants get the same dose every 3 weeks, and researchers check if their cancer shrinks or stops growi…

This study tests whether a precise, high-dose radiation technique (SABR) works better than standard low-dose radiation for people with cancer that has spread to a few spots and is starting to grow again. About 194 adults with solid tumors (not lymphoma or myeloma) will be randoml…

This early-phase trial tests a new treatment called CLIC-2201 for people with certain blood cancers (like lymphoma or leukemia) that have not responded to standard therapy or have returned. The treatment uses a patient's own immune cells, which are modified in a lab to better rec…

This study tests if giving radiation in just 2 sessions works as well as the standard 5 sessions for men with intermediate-risk prostate cancer. The goal is to see if fewer treatments cause fewer side effects and are more convenient, while still controlling the cancer. All partic…

This study looks at whether closely monitoring and controlling blood sugar levels can help people with pancreatic cancer who are receiving chemotherapy. About 50 participants will wear a continuous glucose monitor and be randomly assigned to either tight blood sugar control or st…

This study explores whether cancer patients can drink a radioactive sugar solution instead of receiving it through an IV for PET scans. About 15-24 adults who already had a standard PET scan will get a second scan after drinking the solution. Researchers will check image quality,…

This study tracks 30 adults with rare cancers or rare genetic changes who are already taking a Health Canada-approved targeted therapy that isn't yet covered nationally. Researchers will measure how long patients live, their quality of life, and how well the treatment works. The …

This study looks at whether genetic information from tumors can help doctors choose better treatments for pancreatic cancer. About 200 adults with early or locally advanced pancreatic cancer will give blood, tissue, and fluid samples for genetic testing. Researchers want to see i…

This study is for 100 cancer patients whose treatments have some evidence of working, but doctors aren't sure how much they help or if they're worth the cost. Researchers will track how long patients live and how they feel day-to-day using simple quality-of-life surveys. The goal…

This study aims to understand how gene changes in metastatic pancreatic cancer relate to treatment response. Researchers will analyze tumor samples from 190 adults starting chemotherapy. The goal is to see if returning genetic results within 8 weeks is feasible, which could help …

This study looks at whether tailoring surgery for vulvar cancer based on whether the cancer is linked to HPV or to a p53 gene change can lead to better outcomes. About 249 women with early-stage vulvar squamous cell carcinoma will have their treatment guided by these markers. The…

This study is for people with advanced or metastatic cancers that cannot be cured. Researchers will analyze the full DNA of each person's tumor to find the specific genetic changes driving their cancer. The goal is to see if this information helps doctors choose more effective, t…

This study is for 100 men with low-risk or early intermediate-risk prostate cancer who will receive a type of radiation called HDR brachytherapy. Researchers will use advanced lab tests to see how the radiation changes the cancer's chemistry and the body's immune response. The go…