British Columbia Cancer Agency

This study compares two types of radiation therapy for men with favorable or low-tier intermediate risk prostate cancer: low dose rate (LDR) brachytherapy, which uses permanent radioactive seeds, and high dose rate (HDR) brachytherapy, which uses temporary radioactive material. T…

This study tests whether a precise, high-dose radiation treatment called SABR, when added to standard care, helps people with 1 to 3 metastatic tumors live longer and have a better quality of life. About 330 adults with controlled primary tumors and up to 8 past metastases are pa…

This study tests a one-time radiation treatment for early-stage breast cancer. After a lumpectomy, tiny radioactive seeds are placed directly into the breast to kill any remaining cancer cells. The goal is to see if this method is safe, works well, and costs less than standard da…

This study compares two radiation methods for men with low- or intermediate-risk prostate cancer: low dose rate (permanent seed implants) and high dose rate (temporary radioactive needles). The main goal is to see which approach better preserves urinary quality of life. About 140…

This trial compares two types of brachytherapy boost (HDR vs LDR) given alongside external beam radiation for intermediate- and high-risk prostate cancer. The goal is to see which one provides better cancer control and quality of life with fewer side effects. About 195 men are ta…

This study tests a new radioactive drug, 177Lu-HTK03170, designed to seek out and destroy prostate cancer cells that have spread. It is for men with metastatic castration-resistant prostate cancer whose disease has worsened after other treatments. The trial will first find a safe…

This study tests a precise type of radiation called SABR for people with a limited number of metastatic tumors (up to 5). The goal is to see how well patients tolerate the treatment and how it affects their quality of life and survival. About 399 participants will receive daily o…

This study tests whether a new type of PET/CT scan, using a radioactive tracer called 68Ga-DOTATOC, can find neuroendocrine tumors (NETs) and similar tumors more safely and accurately than current imaging methods. About 800 people with known or suspected NETs will receive the sca…

Researchers are testing whether a one-day course of targeted radiation works as well as the standard five-day course for people whose cancer has spread to the brain. The trial enrolls about 100 adults with brain metastases and a poor prognosis. Everyone receives precise, image-gu…

This study looks at whether a blood test (liquid biopsy) can find cancer mutations as well as the standard tissue biopsy. Researchers will compare the two methods in 1,500 advanced cancer patients to see if the blood test helps doctors choose better treatments and saves money. Th…