Boston Scientific Corporation

This study tracks the safety and effectiveness of the Orbera365 intragastric balloon, a device placed in the stomach to help with weight loss. About 200 obese adults in Europe will be followed during the time the balloon is in place (up to 12 months) and for 30 days after removal…

This study is testing a treatment called BSJ019T in 51 Japanese adults with liver cancer that cannot be removed by surgery and has not responded to or is not suitable for standard treatments. The main goal is to see if the treatment can control the cancer in the liver for at leas…

This study follows 4800 adults who use Boston Scientific neurostimulation devices for chronic pain. It aims to see how well the devices work in everyday life, including pain relief and quality of life. Participants are already scheduled to receive the device as part of their norm…

This study tests a new way to treat persistent atrial fibrillation (a type of irregular heartbeat) using pulsed field ablation, a procedure that destroys tiny areas of heart tissue causing the problem. About 699 adults with persistent AFib that hasn't improved with medication wil…

This study collects information from 500 people with essential tremor who receive a commercially approved deep brain stimulation (DBS) system. Researchers will track changes in quality of life over time using a standard questionnaire. The goal is to understand how well the device…

This study tests a procedure called transoral outlet reduction (TORe) combined with intensive lifestyle changes for people who have regained weight after gastric bypass surgery. About 108 participants will be randomly assigned to either receive the TORe procedure plus lifestyle c…

This study tests whether a device called TheraSphere GBM is safe for people whose glioblastoma brain tumor has come back. It delivers tiny radioactive beads directly to the tumor through blood vessels. The trial will enroll 36 adults and watch for serious side effects like brain …

This study is a registry that will collect real-world information on the safety and success of the WATCHMAN FLX Pro device, which is used to close a part of the heart called the left atrial appendage in people with atrial fibrillation (a type of irregular heartbeat). About 1,000 …

This study is a large registry that will collect information from 5,000 people with peripheral vascular disease (narrowed arteries in the legs). It looks at how well Boston Scientific's drug-coated devices work in everyday medical practice, including in groups often left out of c…

This study tests a new way to treat persistent atrial fibrillation (a type of irregular heartbeat) in people who have already had one ablation procedure. The treatment uses a special system called FARAPULSE to deliver energy to the heart and block faulty signals. About 376 adults…

This registry is collecting information from around the world on how well the Vercise deep brain stimulation (DBS) system works for people with Parkinson's disease. It will include up to 1,500 adults who are already eligible for DBS. The goal is to see if the treatment improves q…

This study looks at 150 adults with obesity who stopped taking GLP-1 weight-loss drugs (like Wegovy or Mounjaro) because of side effects or not losing enough weight. It compares a procedure called endoscopic sleeve gastroplasty (ESG), which reduces stomach size, to lifestyle chan…

This study tests new energy waveforms from the FARAPULSE system to treat atrial fibrillation, a common heart rhythm problem. About 200 adults with either occasional or persistent AFib will receive a minimally invasive procedure to isolate faulty electrical signals in the heart. T…

This study compares two heart procedures for people with persistent atrial fibrillation (a type of irregular heartbeat). One group gets the standard treatment (isolating the pulmonary veins) plus an extra set of ablation lines in the heart, while the other group gets the standard…

This study looks at how safe and effective a new pacemaker lead is when placed in a specific area of the heart (left bundle branch area) to help people with bradycardia (slow heart rate). About 140 people who need a new pacemaker will be followed to see if the lead works well and…

This study tests whether a drug-coated balloon can be a safe and effective alternative to stents for people with coronary artery disease. About 1,600 participants will be randomly assigned to receive either the balloon or standard stent treatment. The goal is to see if the balloo…

This study looks at how well a weight-loss procedure called endoscopic sleeve gastroplasty (ESG) works over the long term. Researchers are following 100 adults who had ESG at least 5 years ago to see if they kept the weight off. The goal is to understand if this minimally invasiv…

This study follows 300 people with dystonia who receive a commercially approved deep brain stimulation system. The goal is to see how well the treatment reduces symptoms like muscle spasms and abnormal postures in everyday medical practice. Participants must be at least 7 years o…

This study looks at how safe and well Boston Scientific's devices work for treating kidney stones and enlarged prostate (BPH). About 238 adults who are already scheduled for these procedures will take part. Researchers will track serious side effects and, for stone patients, how …

This study will follow 500 Chinese adults with paroxysmal atrial fibrillation (a type of irregular heartbeat) who are treated with the FARAPULSE pulsed field ablation system. The goal is to see how well the procedure works and how safe it is in everyday hospital use. Researchers …

This study compares a new pacing method (Left Bundle Branch Area Pacing) with the standard heart failure pacing therapy (Cardiac Resynchronization Therapy) in 850 adults with moderate to severe heart failure. The goal is to see if the new method reduces death, need for heart tran…

This study tests a sponge-based treatment called Endo-SPONGE for people who develop a leak after colorectal surgery. The sponge is placed inside the leak during an endoscopic procedure to help it heal. Researchers will check if the leak closes within 3 months without needing more…

This study tests a new device called FARAFLEX that uses pulsed field ablation to treat people with persistent or occasional atrial fibrillation (an irregular heartbeat). About 250 adults will receive either the new catheter or a standard one to see if it safely and effectively cr…

This study combines two heart procedures into one session for people with atrial fibrillation (AFib). The first uses pulsed field energy to fix the irregular heartbeat, and the second closes a small pouch in the heart to lower stroke risk. About 433 adults who need both treatment…

This study tests a new type of spinal cord stimulation (called TVP-SCS) to see if it can reduce chronic low back and leg pain by at least 50% in 70 adults. Participants must have had pain for 6 months or more and be able to complete English questionnaires. The main goal is to mea…

This study is tracking how well a commercially approved procedure called Intracept works for people with chronic low back pain caused by vertebrogenic pain syndrome. The procedure uses a device to ablate (disable) certain nerves in the spine. Researchers will measure changes in d…

This study will look at anonymous medical records from up to 15,000 adults with chronic pain who have used Boston Scientific devices. The goal is to see how well different treatments relieve pain over time. No new treatments or procedures are given—researchers are just reviewing …

This study looks back at the medical records of up to 5,000 people who have or are eligible for deep brain stimulation (DBS) to treat Parkinson's disease, essential tremor, or dystonia. Researchers want to see how well DBS improves symptoms over time in everyday medical practice.…

This study looks at new software features for mapping abnormal heart rhythms. About 100 adults scheduled for a standard heart mapping procedure will take part. Doctors will give feedback on how well the software works, which may help improve future versions.

This study is collecting information from 200 people with Parkinson's disease, dystonia, essential tremor, or other movement disorders who are scheduled to receive a standard radiofrequency (RF) ablation treatment. The goal is to see how the procedure affects patients' quality of…

This study is a registry that will follow about 12,500 people with heart disease who receive Boston Scientific heart devices (like pacemakers or ablation tools). Its main goal is to track how safe and well the devices work over time, as required by European regulations. Participa…