Brain pacemaker registry tracks Real-Life results for Parkinson's patients
NCT ID NCT02071134
First seen Jun 24, 2026 · Last updated Sep 17, 2026 · Updated 7 times
Summary
This registry is collecting information from 1,500 people with Parkinson's disease who are receiving deep brain stimulation (DBS) with the Vercise system. The goal is to see how DBS affects quality of life in everyday practice, and to evaluate new programming tools. Participants must meet standard criteria for DBS and be at least 18 years old.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Deep brain stimulation (DBS) device
- What this could lead to
- If successful, this registry could help doctors better understand how to use DBS to improve quality of life for people with Parkinson's disease.
- What could go wrong
- This is an observational registry, not a controlled trial, so it cannot prove cause and effect. Results may vary widely among participants.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,500 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2014
- Expected to finish
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Dec 2038
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with symptoms of Parkinson's disease that are not adequately controlled with medication
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Key Inclusion Criteria: * Meets criteria established in locally applicable Vercise System Direction for Use * At least 18 years old Key Exclusion Criteria: * Meets any contraindication in the Vercise System locally applicable Directions for Use Subjects with significant cognitive or psychiatric impairment may be excluded in the evaluation of GXT.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Parkinson's disease are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
34 sites in 8 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Study contacts
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Contact
Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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10 Military Clinical Hospital Bydgoszcz
TERMINATEDBydgoszcz, Poland
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A.o. LKH Univ.-Kliniken Innsbruck
RECRUITINGInnsbruck, Austria
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AZ Delta
ACTIVE_NOT_RECRUITINGRoeselare, Belgium
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AZ Sint-Lucas
ACTIVE_NOT_RECRUITINGGhent, Belgium
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Albany Medical College
COMPLETEDAlbany, New York, 12208, United States
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Azienda Ospedaliero-Universitaria di Ferrara
COMPLETEDFerrara, Italy
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Bahcesehir University Hospital Medical Park Goztepe
RECRUITINGIstanbul, Turkey (Türkiye)
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CHRU Hopital Pontchaillou
WITHDRAWNRennes, France
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CHU Henri Mondor
ACTIVE_NOT_RECRUITINGCréteil, France
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CHU La Timone Hospital
ACTIVE_NOT_RECRUITINGMarseille, France
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Cedars Sinai Medical Center
RECRUITINGLos Angeles, California, 90048, United States
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Centro Especial Ramon y Cajal
COMPLETEDMadrid, Spain
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Centrum Onkologii - Instytut im. Marii Sklodowskiej-Curie
TERMINATEDWarsaw, Poland
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Charing Cross Hospital
RECRUITINGLondon, United Kingdom
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Cleveland Clinic Foundation
TERMINATEDCleveland, Ohio, 44195, United States
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Evangelisches Krankenhaus Oldenburg
RECRUITINGOldenburg, Germany
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Evergreen Health
RECRUITINGKirkland, Washington, 98034, United States
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Fondation Ophtalmologique Adolphe de Rothschild
TERMINATEDParis, France
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Fondazione Istituto Neurologico Casimiro Mondino
COMPLETEDPavia, Italy
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Fundacion Ineco-Research Facility
RECRUITINGBuenos Aires, Argentina
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Hadassah Hebrew University Medical Center
ACTIVE_NOT_RECRUITINGJerusalem, Israel
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Hopital Neurologique Pierre Wertheimer
COMPLETEDLyon, France
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Hopital de Enfant-Jesus
ACTIVE_NOT_RECRUITINGQuébec, Canada
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Hospital Clinic de Barcelona
COMPLETEDBarcelona, Spain
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Hospital Clinico San Carlos
COMPLETEDMadrid, Spain
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Hospital De Bellvitge
ACTIVE_NOT_RECRUITINGBarcelona, Spain
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Hospital General De Asturias
RECRUITINGOviedo, Spain
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Hospital Universitario La Fe
RECRUITINGValencia, Spain
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Houston Methodist Research Institute
RECRUITINGHouston, Texas, 77030, United States
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IRCCS Istituto Ortopedico Galeazzi
TERMINATEDMilan, Italy
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Inland Northwest Research
RECRUITINGSpokane, Washington, 99202, United States
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Johannes Gutenberg Universitaet Mainz
WITHDRAWNMainz, Germany
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John Radcliffe Hospital
COMPLETEDOxford, United Kingdom
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King's College Hospital London
COMPLETEDLondon, United Kingdom
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Koc University Hospital
RECRUITINGIstanbul, Turkey (Türkiye)
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Massachusetts General Hospital
WITHDRAWNBoston, Massachusetts, 02114, United States
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Mayo Clinic, Jacksonville
WITHDRAWNJacksonville, Florida, 32224, United States
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Medical School of University PECS
ACTIVE_NOT_RECRUITINGPécs, Hungary
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Methodist Hospital of Indianapolis
COMPLETEDIndianapolis, Indiana, 46202, United States
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Neurology and Pain Specialty
WITHDRAWNAliso Viejo, California, 92656, United States
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Northwell Health Neuroscience Institute
RECRUITINGGreat Neck, New York, 11021, United States
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Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
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Osp. S. Maria Della Misericordia
TERMINATEDUdine, Italy
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Ospedale Dell Angelo
TERMINATEDMestre, Italy
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Podmiot Leczniczy Copernicus Sp. z o.o.
COMPLETEDGdansk, Poland
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Policlinico Universitario Agostino Gemelli
RECRUITINGRome, Italy
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Queen Elizabeth II Health Sciences Center
ACTIVE_NOT_RECRUITINGHalifax, Canada
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Queen Elizabeth University Hospital
ACTIVE_NOT_RECRUITINGGlasgow, United Kingdom
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Royal Victoria Infirmary
ACTIVE_NOT_RECRUITINGNewcastle, United Kingdom
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Rush University Medical Center
RECRUITINGChicago, Illinois, 60612, United States
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Samsung Medical Center
ACTIVE_NOT_RECRUITINGSeoul, South Korea
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Seoul ASAN Medical Center
TERMINATEDSeoul, South Korea
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Sheba Medical Center
COMPLETEDTel Litwinsky, Israel
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Southmead Hospital Bristol
COMPLETEDBristol, United Kingdom
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St. Barbara-Klinik Hamm-Heessen
WITHDRAWNHamm, Germany
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St. Georges Hospital
COMPLETEDLondon, United Kingdom
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St. Louis University Hospital
WITHDRAWNSt Louis, Missouri, 63110, United States
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St. Luke Regional Medical Center
RECRUITINGBoise, Idaho, 83702, United States
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St. Mary's Hospital and Medical Center
RECRUITINGGrand Junction, Colorado, 81501, United States
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Tallahassee Neurological Clinic, PA
WITHDRAWNTallahassee, Florida, 32308, United States
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Tel Aviv Sourasky Medical Center
COMPLETEDTel Aviv, Israel
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Texas Institute for Neurological Disorders
RECRUITINGSherman, Texas, 75092, United States
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The Walton Centre
COMPLETEDLiverpool, United Kingdom
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UZ Gasthuisberg
ACTIVE_NOT_RECRUITINGLeuven, Belgium
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Uniklinik Köln
COMPLETEDCologne, Germany
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Universitaetsklinikum Giessen und Marburg GmbH
RECRUITINGMarburg, Germany
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University Berlin, Charite Virchow Standort, Wedding
RECRUITINGBerlin, Germany
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University Hospital Virgen Arrixaca
WITHDRAWNMurcia, Spain
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University at Buffalo
RECRUITINGWilliamsville, New York, 14221, United States
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University of Colorado
RECRUITINGAurora, Colorado, 80220, United States
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University of Florida Shands Hospital
RECRUITINGGainesville, Florida, 32610, United States
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University of Miami Hospital
RECRUITINGMiami, Florida, 33136, United States
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University of South Florida
RECRUITINGTampa, Florida, 33612, United States
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University of Texas Health Medical Arts and Research Center
RECRUITINGSan Antonio, Texas, 78229, United States
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University of Virginia Medical Center
WITHDRAWNCharlottesville, Virginia, 22903, United States
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University of Washington Medical Center
RECRUITINGSeattle, Washington, 98195, United States
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Universitätsklinik Eppendorf
RECRUITINGHamburg, Germany
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Universitätsklinikum Campus Kiel
RECRUITINGKiel, Germany
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Universitätsklinikum Düsseldorf
RECRUITINGDüsseldorf, Germany
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Universitätsklinikum Freiburg
ACTIVE_NOT_RECRUITINGFreiburg im Breisgau, Germany
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Universitätsklinikum Würzburg
RECRUITINGWürzburg, Germany
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Vanderbilt University
WITHDRAWNNashville, Tennessee, 37232, United States
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Villa Margherita
TERMINATEDArcugnano, Italy
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Virginia Mason Medical Center
RECRUITINGSeattle, Washington, 98101, United States
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Wake Forest University School of Medicine
RECRUITINGWinston-Salem, North Carolina, 27157, United States
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Yonsei University Severance Hospital
COMPLETEDSeoul, South Korea
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Walking memory tests may reveal early Parkinson's clues
- Colon tissue may hold clues to telling Parkinson's apart from Look-Alike diseases
- A genetic roadmap for Parkinson's: testing thousands to unlock clues
- Can gentle touch therapy calm Parkinson's tremors?
- Stem cell infusions aim to slow Parkinson's progression
- Can an inhaled levodopa ease Parkinson's OFF episodes? a study asks patients.