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Brain pacemaker registry tracks Real-Life results for Parkinson's patients

NCT ID NCT02071134

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Sep 17, 2026 · Updated 7 times

Summary

This registry is collecting information from 1,500 people with Parkinson's disease who are receiving deep brain stimulation (DBS) with the Vercise system. The goal is to see how DBS affects quality of life in everyday practice, and to evaluate new programming tools. Participants must meet standard criteria for DBS and be at least 18 years old.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Deep brain stimulation (DBS) device
What this could lead to
If successful, this registry could help doctors better understand how to use DBS to improve quality of life for people with Parkinson's disease.
What could go wrong
This is an observational registry, not a controlled trial, so it cannot prove cause and effect. Results may vary widely among participants.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 1,500 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2014

Expected to finish

Dec 2038

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with symptoms of Parkinson's disease that are not adequately controlled with medication

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Key Inclusion Criteria: * Meets criteria established in locally applicable Vercise System Direction for Use * At least 18 years old Key Exclusion Criteria: * Meets any contraindication in the Vercise System locally applicable Directions for Use Subjects with significant cognitive or psychiatric impairment may be excluded in the evaluation of GXT.

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Get notified about this study

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    34 sites in 8 countries. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • 10 Military Clinical Hospital Bydgoszcz

    TERMINATED

    Bydgoszcz, Poland

  • A.o. LKH Univ.-Kliniken Innsbruck

    RECRUITING

    Innsbruck, Austria

  • AZ Delta

    ACTIVE_NOT_RECRUITING

    Roeselare, Belgium

  • AZ Sint-Lucas

    ACTIVE_NOT_RECRUITING

    Ghent, Belgium

  • Albany Medical College

    COMPLETED

    Albany, New York, 12208, United States

  • Azienda Ospedaliero-Universitaria di Ferrara

    COMPLETED

    Ferrara, Italy

  • Bahcesehir University Hospital Medical Park Goztepe

    RECRUITING

    Istanbul, Turkey (Türkiye)

  • CHRU Hopital Pontchaillou

    WITHDRAWN

    Rennes, France

  • CHU Henri Mondor

    ACTIVE_NOT_RECRUITING

    Créteil, France

  • CHU La Timone Hospital

    ACTIVE_NOT_RECRUITING

    Marseille, France

  • Cedars Sinai Medical Center

    RECRUITING

    Los Angeles, California, 90048, United States

  • Centro Especial Ramon y Cajal

    COMPLETED

    Madrid, Spain

  • Centrum Onkologii - Instytut im. Marii Sklodowskiej-Curie

    TERMINATED

    Warsaw, Poland

  • Charing Cross Hospital

    RECRUITING

    London, United Kingdom

  • Cleveland Clinic Foundation

    TERMINATED

    Cleveland, Ohio, 44195, United States

  • Evangelisches Krankenhaus Oldenburg

    RECRUITING

    Oldenburg, Germany

  • Evergreen Health

    RECRUITING

    Kirkland, Washington, 98034, United States

  • Fondation Ophtalmologique Adolphe de Rothschild

    TERMINATED

    Paris, France

  • Fondazione Istituto Neurologico Casimiro Mondino

    COMPLETED

    Pavia, Italy

  • Fundacion Ineco-Research Facility

    RECRUITING

    Buenos Aires, Argentina

  • Hadassah Hebrew University Medical Center

    ACTIVE_NOT_RECRUITING

    Jerusalem, Israel

  • Hopital Neurologique Pierre Wertheimer

    COMPLETED

    Lyon, France

  • Hopital de Enfant-Jesus

    ACTIVE_NOT_RECRUITING

    Québec, Canada

  • Hospital Clinic de Barcelona

    COMPLETED

    Barcelona, Spain

  • Hospital Clinico San Carlos

    COMPLETED

    Madrid, Spain

  • Hospital De Bellvitge

    ACTIVE_NOT_RECRUITING

    Barcelona, Spain

  • Hospital General De Asturias

    RECRUITING

    Oviedo, Spain

  • Hospital Universitario La Fe

    RECRUITING

    Valencia, Spain

  • Houston Methodist Research Institute

    RECRUITING

    Houston, Texas, 77030, United States

  • IRCCS Istituto Ortopedico Galeazzi

    TERMINATED

    Milan, Italy

  • Inland Northwest Research

    RECRUITING

    Spokane, Washington, 99202, United States

  • Johannes Gutenberg Universitaet Mainz

    WITHDRAWN

    Mainz, Germany

  • John Radcliffe Hospital

    COMPLETED

    Oxford, United Kingdom

  • King's College Hospital London

    COMPLETED

    London, United Kingdom

  • Koc University Hospital

    RECRUITING

    Istanbul, Turkey (Türkiye)

  • Massachusetts General Hospital

    WITHDRAWN

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic, Jacksonville

    WITHDRAWN

    Jacksonville, Florida, 32224, United States

  • Medical School of University PECS

    ACTIVE_NOT_RECRUITING

    Pécs, Hungary

  • Methodist Hospital of Indianapolis

    COMPLETED

    Indianapolis, Indiana, 46202, United States

  • Neurology and Pain Specialty

    WITHDRAWN

    Aliso Viejo, California, 92656, United States

  • Northwell Health Neuroscience Institute

    RECRUITING

    Great Neck, New York, 11021, United States

  • Ohio State University

    RECRUITING

    Columbus, Ohio, 43210, United States

  • Osp. S. Maria Della Misericordia

    TERMINATED

    Udine, Italy

  • Ospedale Dell Angelo

    TERMINATED

    Mestre, Italy

  • Podmiot Leczniczy Copernicus Sp. z o.o.

    COMPLETED

    Gdansk, Poland

  • Policlinico Universitario Agostino Gemelli

    RECRUITING

    Rome, Italy

  • Queen Elizabeth II Health Sciences Center

    ACTIVE_NOT_RECRUITING

    Halifax, Canada

  • Queen Elizabeth University Hospital

    ACTIVE_NOT_RECRUITING

    Glasgow, United Kingdom

  • Royal Victoria Infirmary

    ACTIVE_NOT_RECRUITING

    Newcastle, United Kingdom

  • Rush University Medical Center

    RECRUITING

    Chicago, Illinois, 60612, United States

  • Samsung Medical Center

    ACTIVE_NOT_RECRUITING

    Seoul, South Korea

  • Seoul ASAN Medical Center

    TERMINATED

    Seoul, South Korea

  • Sheba Medical Center

    COMPLETED

    Tel Litwinsky, Israel

  • Southmead Hospital Bristol

    COMPLETED

    Bristol, United Kingdom

  • St. Barbara-Klinik Hamm-Heessen

    WITHDRAWN

    Hamm, Germany

  • St. Georges Hospital

    COMPLETED

    London, United Kingdom

  • St. Louis University Hospital

    WITHDRAWN

    St Louis, Missouri, 63110, United States

  • St. Luke Regional Medical Center

    RECRUITING

    Boise, Idaho, 83702, United States

  • St. Mary's Hospital and Medical Center

    RECRUITING

    Grand Junction, Colorado, 81501, United States

  • Tallahassee Neurological Clinic, PA

    WITHDRAWN

    Tallahassee, Florida, 32308, United States

  • Tel Aviv Sourasky Medical Center

    COMPLETED

    Tel Aviv, Israel

  • Texas Institute for Neurological Disorders

    RECRUITING

    Sherman, Texas, 75092, United States

  • The Walton Centre

    COMPLETED

    Liverpool, United Kingdom

  • UZ Gasthuisberg

    ACTIVE_NOT_RECRUITING

    Leuven, Belgium

  • Uniklinik Köln

    COMPLETED

    Cologne, Germany

  • Universitaetsklinikum Giessen und Marburg GmbH

    RECRUITING

    Marburg, Germany

  • University Berlin, Charite Virchow Standort, Wedding

    RECRUITING

    Berlin, Germany

  • University Hospital Virgen Arrixaca

    WITHDRAWN

    Murcia, Spain

  • University at Buffalo

    RECRUITING

    Williamsville, New York, 14221, United States

  • University of Colorado

    RECRUITING

    Aurora, Colorado, 80220, United States

  • University of Florida Shands Hospital

    RECRUITING

    Gainesville, Florida, 32610, United States

  • University of Miami Hospital

    RECRUITING

    Miami, Florida, 33136, United States

  • University of South Florida

    RECRUITING

    Tampa, Florida, 33612, United States

  • University of Texas Health Medical Arts and Research Center

    RECRUITING

    San Antonio, Texas, 78229, United States

  • University of Virginia Medical Center

    WITHDRAWN

    Charlottesville, Virginia, 22903, United States

  • University of Washington Medical Center

    RECRUITING

    Seattle, Washington, 98195, United States

  • Universitätsklinik Eppendorf

    RECRUITING

    Hamburg, Germany

  • Universitätsklinikum Campus Kiel

    RECRUITING

    Kiel, Germany

  • Universitätsklinikum Düsseldorf

    RECRUITING

    Düsseldorf, Germany

  • Universitätsklinikum Freiburg

    ACTIVE_NOT_RECRUITING

    Freiburg im Breisgau, Germany

  • Universitätsklinikum Würzburg

    RECRUITING

    Würzburg, Germany

  • Vanderbilt University

    WITHDRAWN

    Nashville, Tennessee, 37232, United States

  • Villa Margherita

    TERMINATED

    Arcugnano, Italy

  • Virginia Mason Medical Center

    RECRUITING

    Seattle, Washington, 98101, United States

  • Wake Forest University School of Medicine

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

  • Yonsei University Severance Hospital

    COMPLETED

    Seoul, South Korea

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