Biontech Se

This large, completed Phase 3 trial aimed to evaluate the safety and effectiveness of additional 'booster' doses of the Pfizer-BioNTech COVID-19 vaccine. It involved over 16,000 healthy participants, aged 12 and older, who had already received their initial vaccine series. The st…

This early-stage clinical trial tested a new RNA-based vaccine designed to protect against mpox (monkeypox). The study enrolled 96 healthy adults, some who had received a smallpox vaccine decades ago and some who had not. Researchers primarily measured the vaccine's safety, side …

This study tested new mRNA vaccines designed to protect against both influenza (flu) and COVID-19. Researchers gave healthy adults a single shot containing either a flu vaccine, a COVID-19 vaccine, or a mix of both to see how safe they were and how well they triggered an immune r…

This study tested new versions of COVID-19 booster shots designed to protect against newer virus strains. It involved over 1,400 healthy people who had already received their initial COVID-19 vaccines. Researchers gave participants a single dose of an updated booster and then mon…

This study tested the safety and immune response of the Pfizer-BioNTech COVID-19 vaccine in 960 healthy Chinese adults. Participants received either two doses of the vaccine or a placebo shot, with researchers tracking their antibody levels and any side effects for about a year. …

This early-stage trial tested the safety of two new tuberculosis vaccine candidates in healthy adults who had never received the standard BCG vaccine. Researchers gave 120 participants different dose levels of the experimental vaccines or a placebo to check for side effects and i…

This large study tested several versions of an mRNA vaccine to prevent COVID-19. It involved nearly 47,000 healthy volunteers, including teenagers and older adults. The main goal was to find the safest and most effective dose and schedule, leading to the authorization of the wide…

This early-stage trial tested a new investigational RNA-based COVID-19 vaccine, called BNT162b4, in 383 healthy adults who had already received previous COVID-19 shots. The main goal was to check the safety and side effects of different doses, given alone or combined with existin…

This was a first-in-human study to test the safety and immune response of a new RNA-based malaria vaccine called BNT165b1. The trial enrolled 60 healthy adults to receive one of three dose levels or a placebo. The main goal was to find a safe and tolerable dose for future develop…

This large, completed Phase 3 trial tested a new single vaccine designed to protect against both COVID-19 and seasonal influenza. Nearly 9,000 healthy adults received either the combined shot or separate standard vaccines to compare safety and immune response. The goal is to see …

This study tested whether combining a new cancer vaccine (BNT111) with an existing immunotherapy drug (cemiplimab) could help patients with advanced skin cancer (melanoma) that had stopped responding to standard treatments. 184 adults with stage III or IV melanoma were assigned t…

This Phase 1 trial tested two personalized RNA vaccines designed to train the immune system to attack triple-negative breast cancer cells. The study involved 42 patients who had completed standard treatments like surgery and chemotherapy. Researchers created custom vaccines for e…

This was the first-ever study in people to test the safety and early effects of two new cancer drugs, BNT152 and BNT153, developed by BioNTech. It involved 86 adults with advanced solid tumors that had spread or could not be removed by surgery, and for whom standard treatments we…