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This study tested updated mRNA vaccines designed to protect against new COVID-19 variants. Over 1,000 healthy people aged 12 and older received a single dose. Researchers monitored side effects and measured immune responses to see how well the vaccines worked.

This study tested a single combined vaccine that aims to protect against both COVID-19 and influenza. Around 8,800 healthy adults received either the combo shot or separate vaccines. Researchers checked for side effects and immune response over 6 months. The goal is to make vacci…

This large study tested the safety and effectiveness of the Pfizer-BioNTech COVID-19 vaccine in nearly 47,000 healthy volunteers aged 12 and older. Participants received two doses of the vaccine or a placebo, and researchers tracked how many got COVID-19. The vaccine proved highl…

This study tested whether a single shot combining modified RNA vaccines for flu and COVID-19 is safe and works well. About 2,650 healthy adults aged 18 and older received one injection of either a flu vaccine, a COVID-19 vaccine, or both combined. Researchers monitored side effec…

This early-stage trial tested two experimental vaccines (BNT164a1 and BNT164b1) against tuberculosis in 120 healthy adults who had never received a TB vaccine or been exposed to TB. The main goal was to check safety and find the best dose. Participants received three shots and we…

This study tested several updated COVID-19 booster vaccines in over 1,400 healthy people aged 12 and older who had already received prior COVID-19 vaccines. The goal was to see if these new boosters were safe and could improve the body's immune response against newer virus varian…

This large study tested whether giving extra doses (boosters) of the Pfizer-BioNTech COVID-19 vaccine to healthy people who already had the vaccine is safe and helps prevent COVID-19. Over 16,000 people took part, and the study looked at different booster schedules and doses. The…

This study tested a COVID-19 mRNA vaccine (BNT162b2) in 960 healthy Chinese adults aged 18 to 85. Participants received two shots, 21 days apart, and were monitored for about 13 months. The main goal was to check safety and how well the vaccine triggered an immune response. Resul…

This early-stage trial tested an experimental RNA-based malaria vaccine in 60 healthy adults. The goal was to check if the vaccine is safe and triggers an immune response. Researchers gave three different dose levels to find the best one for future studies.

This study tested a new RNA-based vaccine (BNT166a) to prevent mpox (formerly monkeypox). It involved 96 healthy adults and looked at safety and how well the vaccine triggers the immune system. The trial was completed and helps determine if the vaccine is safe enough for further …

This study tested an experimental RNA-based vaccine (BNT165e) designed to prevent malaria caused by the P. falciparum parasite. 163 healthy adults who had never had malaria received the vaccine, and researchers checked for side effects, immune response, and whether the vaccine co…

This early-stage study tested a new RNA-based COVID-19 booster vaccine (BNT162b4) in 383 healthy adults who had already received a COVID-19 vaccine. The goal was to find a safe dose and see how well the vaccine boosts the immune system. Participants received either the new vaccin…

This early-phase study tested a new RNA-based cancer vaccine in 119 people with advanced melanoma. The vaccine targets four proteins found on melanoma cells to train the immune system to fight the cancer. The main goal was to check safety and find the right dose, with early signs…

This study tested a new cancer vaccine (BNT111) combined with an immunotherapy drug (cemiplimab) in 184 people with advanced melanoma that had stopped responding to prior treatment. The goal was to see if the combination could shrink tumors better than either treatment alone. Par…

This early-phase study tested personalized RNA vaccines designed to train the immune system to attack each patient's unique tumor. 42 people with triple negative breast cancer received custom-made vaccines. The main goal was to check safety and see if the vaccines triggered an im…

This early-phase trial tested two experimental drugs, BNT152 and BNT153, in 86 adults with advanced solid tumors that had spread or could not be removed and had no standard treatment options. The main goal was to check safety and find the right dose. Researchers also looked for s…