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New cancer combo shows promise in early trial for Hard-to-Treat tumors

NCT ID NCT04710043

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 24 times

Summary

This early-phase trial tested two experimental drugs, BNT152 and BNT153, in 86 adults with advanced solid tumors that had spread or could not be removed and had no standard treatment options. The main goal was to check safety and find the right dose. Researchers also looked for signs that the drugs could shrink tumors or control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Duke Cancer Center

    Durham, North Carolina, 27710, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Masaryk Memorial Cancer Institute

    Brno, 65653, Czechia

  • NEXT Oncology

    San Antonio, Texas, 78229, United States

  • Robert H. Lurie Comprehensive Cancer Center, Northwestern University

    Chicago, Illinois, 60611, United States

  • Sarah Cannon Research Institute at Tennessee Oncology

    Nashville, Tennessee, 37203, United States

  • Yale Cancer Center

    New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.