Beth Israel Deaconess Medical Center

This phase 2 trial tests a personalized vaccine made from a patient's own immune cells fused with their tumor cells, given alongside GM-CSF injections and imiquimod cream. The goal is to see if this combination can trigger a stronger immune response against ovarian, fallopian tub…

This study investigates whether Botox injections can lower seizure frequency and severity in adults with drug-resistant focal epilepsy. Researchers will measure changes in brain excitability and quality of life after treatment. The approach is based on shared features between epi…

This pilot study tested the drug deucravacitinib against a placebo in people with moderate-to-severe hidradenitis suppurativa, a chronic skin condition causing painful lumps. Only 7 people enrolled before the study was stopped early. The goal was to see if the drug could reduce i…

This study tested a new microwave device used through a thin tube to destroy tumors blocking the main airways in people with lung cancer. Only 3 patients were enrolled before the study was stopped. The goal was to see if the device could safely and effectively open the airway.

This study looked at whether fremanezumab (Ajovy), an FDA-approved monthly injection for migraine prevention, could also improve sleep in people with migraines. Researchers planned to track 22 participants over 4 months, comparing their migraine days and sleep quality before and …

Researchers are testing a nonlinear microscope (NLM) that images breast tissue during lumpectomy without the usual slide preparation. The goal is to see if the NLM can help surgeons find close or positive margins right away, so fewer patients need a second operation. The trial en…

This study tested whether a non-invasive brain stimulation technique called TMS could help reduce negative symptoms of schizophrenia, like low motivation and reduced facial expression. The trial enrolled 47 adults with schizophrenia or schizoaffective disorder and compared active…

This study tested a special device called the Traxi panniculus retractor, which holds excess belly tissue out of the way during cesarean deliveries. The goal was to see if it could shorten surgery time, improve breathing, and increase satisfaction for both patients and doctors. T…

This study tested whether crofelemer, a drug that reduces fluid secretion in the gut, could improve stool consistency in adults with functional diarrhea. The trial was terminated early after enrolling only 17 participants. The main goal was to measure stool firmness after 4 weeks…

This study aimed to see if a simple eye scan could predict which people with early schizophrenia would benefit from a drug called sodium nitroprusside. The drug was given to reduce psychosis symptoms like delusions and hallucinations. Only one person enrolled before the study was…

This study aimed to see if skipping a type of muscle relaxant during general anesthesia could lower the risk of serious lung complications in high-risk surgery patients. The trial was terminated early after enrolling only 3 participants, so no meaningful conclusions can be drawn.…

This study looked at whether a special pressure measurement (esophageal pressure) can be used during surgeries where only one lung is ventilated. Six adults having non-cardiac surgery participated. Researchers compared the pressure readings to lung collapse images from a device c…

This study tested a non-invasive blood pressure monitor (CNAP) against the standard invasive method (using a needle in the artery) in 20 pregnant women with placenta accreta undergoing scheduled C-sections. The goal was to see if the gentler method gives equally accurate readings…

This study tested a device called a durometer that measures skin elasticity in people with lymphedema. The goal was to see if the device could help track disease progression. Only 7 people took part, and the study was stopped early.