Alliance For Clinical Trials In Oncology

This study aimed to find out if a less extensive surgery (sublobar resection) works as well as the standard surgery (lobectomy) for people with small, early-stage lung cancer. It involved 701 participants who were randomly assigned to receive one of the two surgical procedures. T…

This study tested whether combining two existing cancer drugs—sorafenib and bevacizumab (Avastin)—could help control advanced colorectal cancer that had stopped responding to standard treatments. The trial involved 83 patients whose cancer had spread and progressed despite previo…

This study tested whether adding the drug bortezomib after a strong treatment regimen and a stem cell transplant could help people with newly diagnosed mantle cell lymphoma. The main goal was to see if this extra step could keep the cancer from coming back for a longer period. Re…

This study tested whether adding a breast MRI scan to the standard pre-surgery imaging (mammogram and ultrasound) helps doctors plan better surgery for women with early-stage breast cancer. It aimed to see if the extra scan leads to fewer cancer recurrences, fewer repeat surgerie…