Ahs Cancer Control Alberta

This study compares two ways of using thyroid hormone medication to suppress TSH in people with advanced thyroid cancer that has spread or returned. The standard approach keeps TSH very low (below 0.1), but this can cause side effects. The study will test if a slightly higher TSH…

This study tests whether a chemotherapy drug (temozolomide) works better alone or combined with another drug (olaparib) for people with a specific type of triple-negative breast cancer that has spread or cannot be removed. About 40 adults with a genetic marker called MGMT methyla…

This study tests whether using PSMA-PET scans to guide radiation therapy can improve cancer control in men with high-risk prostate cancer that hasn't spread to lymph nodes. About 250 participants will receive radiation to the prostate and nearby tissues, with or without whole pel…

This study tests a new way to give radiotherapy for prostate cancer. Instead of many treatments, it uses just 2, with the second dose adjusted based on how the tumor responds to the first. The goal is to see if this personalized approach is safe and effective for men with interme…

This study is for people with esophageal cancer that has spread to a few other parts of the body. It tests whether adding a special high-dose radiation treatment (SBRT) to standard chemotherapy and immunotherapy can help control the disease longer. About 22 adults will take part.…

This study tests if giving immunotherapy (pembrolizumab) in the morning works better than giving it at random times for people with advanced non-small cell lung cancer. About 58 participants will be split into two groups: one gets infusions only between 8-10 AM, the other gets th…