Can allergy med stop bone pain in stem cell transplants?
NCT ID NCT05421416
First seen Feb 05, 2026 · Last updated Jun 19, 2026 · Updated 17 times
Summary
This study tests whether the allergy drug loratadine can prevent bone pain caused by G-CSF, a medicine used to collect stem cells for transplant. About 78 adults with lymphoma or multiple myeloma will receive either loratadine or a placebo. The goal is to see if loratadine reduces pain severity and daily-life interference.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cross Cancer Institute
RECRUITINGEdmonton, Alberta, T6G 1Z2, Canada
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Loratadine
What this could lead to
If it works, this could offer a simple, over-the-counter way to prevent bone pain during stem cell collection.
What could go wrong
This is a small, early-phase trial with only 78 participants, so results may not apply widely. Loratadine may not reduce pain better than a placebo.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.