VULVAR CANCER
Clinical trials for VULVAR CANCER explained in plain language.
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New hope for advanced vulvar cancer: triple therapy shows promise
Disease control OngoingThis study tests a combination of standard chemotherapy (cisplatin), an immunotherapy drug (pembrolizumab), and radiation therapy for people with vulvar cancer that cannot be removed by surgery. The goal is to see if this triple therapy can shrink or control the cancer better tha…
Matched conditions: VULVAR CANCER
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 26, 2026 03:21 UTC
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Can a Two-Drug punch wake up 'Cold' tumors?
Disease control TerminatedThis study tests whether combining two drugs—atezolizumab (an immunotherapy) and tivozanib (a targeted therapy)—can shrink tumors in cancers that typically don't respond to immunotherapy alone. About 29 adults with advanced bile duct, gallbladder, breast, neuroendocrine, ovarian,…
Matched conditions: VULVAR CANCER
Phase: PHASE1, PHASE2 • Sponsor: University of Florida • Aim: Disease control
Last updated May 26, 2026 03:10 UTC
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New hope for advanced cancers: immunotherapy drug shows promise in large trial
Disease control OngoingThis study tests the drug pembrolizumab in about 1,600 people with advanced solid tumors that have not responded to standard treatments. The goal is to see if the drug can shrink tumors and to identify biomarkers that predict response. Participants receive pembrolizumab and are m…
Matched conditions: VULVAR CANCER
Phase: PHASE2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated May 26, 2026 03:04 UTC
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New Triple-Drug attack aims to shrink Hard-to-Treat cancers
Disease control OngoingThis study tests a combination of three drugs (entinostat, PDS01ADC, and bintrafusp alfa) in adults with advanced cancers linked to HPV or certain colon cancers that haven't responded to standard treatments. The goal is to find a safe dose and see if the treatment can shrink tumo…
Matched conditions: VULVAR CANCER
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 19, 2026 11:48 UTC
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New imaging technique could improve lymph node detection in vulvar cancer surgery
Diagnosis OngoingThis study compares a newer imaging method using indocyanine green (ICG) with the standard method to find sentinel lymph nodes in people with early-stage vulvar cancer. About 22 participants will receive both imaging techniques during their planned surgery. The goal is to see if …
Matched conditions: VULVAR CANCER
Phase: NA • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Diagnosis
Last updated May 26, 2026 03:04 UTC
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New program aims to slash cancer diagnosis delays in botswana
Knowledge-focused OngoingThis study tests a program called Potlako+ that combines community education, help for healthcare workers, and patient guides to speed up cancer detection and treatment. About 874 adults in Botswana with possible cancer symptoms will take part. Half of the communities get the pro…
Matched conditions: VULVAR CANCER
Phase: PHASE2 • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 03:15 UTC
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Blood test may tame Chemo's nerve pain
Knowledge-focused TerminatedThis study looks at whether regularly measuring the amount of paclitaxel (a chemotherapy drug) in the blood can help doctors give the right dose to kill cancer while limiting nerve damage. About 22 adults with various solid tumors (like lung, breast, or ovarian cancer) will have …
Matched conditions: VULVAR CANCER
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated May 26, 2026 03:12 UTC
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Mid-Treatment PET scans could Fine-Tune radiation for cancer patients
Knowledge-focused OngoingThis study explores whether doing a PET scan during radiation therapy can help doctors adjust the treatment plan to improve outcomes for people with cervical, vulvar, esophageal, or anal cancer. About 90 adults will receive standard radiation plus an extra PET scan partway throug…
Matched conditions: VULVAR CANCER
Phase: PHASE2 • Sponsor: Duke University • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC