VITILIGO

This study tested whether a newer cream (ruxolitinib) works better alone or when combined with two older creams (tacrolimus and steroids) for vitiligo. 120 adults with small patches of vitiligo were treated for 24 weeks. The goal was to see which approach restores more skin color…

This study tested whether adding the cholesterol-lowering drug atorvastatin to standard UVB light therapy works better than UVB alone for active vitiligo. 28 adults with active non-segmental vitiligo took part. The goal was to see if the combination could reduce the amount of whi…

This study tested whether adding methotrexate to UVB light therapy works better than light therapy alone for adults with active, spreading vitiligo. Thirty-two participants were randomly assigned to one of two groups and followed for 4 months. The main goal was to measure changes…

This study tested a drug called AMG 714 in 60 adults with vitiligo, a condition that causes white patches on the skin. The goal was to see if the drug could reduce facial patches by at least 35% after 24 weeks. Participants received either the drug or a placebo, and all were aske…

This study tested the safety and effectiveness of tofacitinib, a drug that blocks certain immune signals, for treating skin conditions like eczema and psoriasis in people with Down syndrome. 47 adolescents and adults took part. The goal was to see if the drug could improve these …

This study tested whether adding the drug apremilast to standard UVB light therapy helps restore skin color in people with vitiligo, a condition that causes white patches. Eighty adults with moderate to severe vitiligo received UVB light twice a week for 24 weeks, plus either apr…

This study tested whether starting treatment early in vitiligo can stop the immune system from attacking skin cells and improve repigmentation. 51 adults with different stages of vitiligo received a combination of light therapy (narrowband UVB) and low-dose steroid pills for 6 mo…

This study tested whether adding baricitinib (a pill) to standard light therapy works better than light therapy alone for adults with active, spreading vitiligo. 49 participants were followed for 12 weeks to measure changes in skin color using a scoring tool. The goal was to see …

This study tested whether adding a special antioxidant pill (GLISODIN) to standard UVB light therapy helps treat vitiligo better than light therapy alone. Fifty adults with non-segmental vitiligo covering more than 5% of their body took part. The main goal was to see if the combi…

This study tested whether blue light therapy or targeted UVB light works better to restore color in stable vitiligo patches. Thirty adults with small, stable white patches received one of the two light treatments. The goal was to see which light type leads to more repigmentation …

This study looked at why vitiligo repigmentation varies by body location. Researchers compared skin samples from 20 people with and without vitiligo to understand what factors in the skin might block repigmentation in hard-to-treat areas like hands and feet. The goal was to gathe…

This study used health records from over 36,000 adults in the UK to see if people with vitiligo are more likely to have mental health problems like depression, anxiety, or self-harm. Researchers compared people with vitiligo to similar people without it. The goal was to understan…

This study tested specially engineered versions of a natural immune protein (IL-2) in blood samples from 67 people with autoimmune or inflammatory diseases like lupus, multiple sclerosis, and rheumatoid arthritis. The goal was to see if these modified proteins could selectively a…