VAGINAL CANCER

This study is testing whether custom 3D-printed devices can improve a type of internal radiation therapy for gynecologic cancers. Researchers will treat 10 patients with cancers of the uterus, vagina, or vulva using these personalized applicators. They aim to see if this new meth…

This study is observing how well the drug T-DXd works for people with advanced HER2-positive cancers who have already tried other treatments and have no good options left. It will follow about 100 patients in real-world US clinics to see how their tumors respond and how long the …

This study is testing the safety and effectiveness of a new investigational drug called GI-101 for people with advanced or metastatic solid tumors. The drug is designed to work in two ways to help the immune system fight cancer. Researchers will test it alone and in combination w…

This study is testing whether the oral drug belzutifan can help control recurrent clear cell cancers of the ovary, uterus, cervix, and other gynecologic sites. It will enroll 32 adults who have already received platinum-based chemotherapy. Researchers will measure how well the dr…

This study is testing whether using MRI scans instead of CT scans to guide radiation therapy for gynecologic cancers can reduce side effects and improve treatment accuracy. Researchers at Johns Hopkins will compare how well MRI helps doctors target tumors while sparing healthy or…

This study is testing a new personalized treatment for advanced cancers caused by HPV. Doctors take a patient's own immune cells, modify them in a lab to better target the cancer, and infuse them back to try to shrink tumors before standard therapy like chemo or surgery. The goal…

This study is testing a new gene therapy for people with advanced cancers caused by HPV. Doctors take a patient's own immune cells, modify them in a lab to better recognize and attack HPV-infected cancer cells, and then infuse them back into the patient. The goal is to see if thi…

This study is building a large, long-term database of health information and biological samples from people with cancer, people at risk for cancer, and healthy volunteers. The goal is to collect this data to help researchers better understand what causes cancer and how to prevent…