UNIPOLAR DEPRESSION

This study tests whether practicing Tao Calligraphy meditation and drinking energized water can improve symptoms of unipolar depression in adults. Fifty participants will be split into two groups to compare the effects over 12 weeks. The goal is to see if these practices can impr…

This study looks at whether a specific yoga practice can help improve thinking skills, like memory and attention, in people whose depression is in remission. About 32 adults aged 18-60 will either do yoga or continue their usual care. The goal is to see if yoga can help with ling…

This study tests a device that sends mild electrical currents to the brain (tDCS) while people practice mindfulness, all done remotely via video calls. The goal is to see if this combination can reduce depression symptoms in 25 adults with major depressive disorder. Participants …

This study tests whether psilocybin, a substance from certain mushrooms, combined with talk therapy can safely help treat major depression in people with non-small cell lung cancer. About 10 participants will receive the drug and be monitored for side effects, suicidal thoughts, …

This study tests whether enoxolone, a compound from licorice, can improve depression symptoms in people with unipolar depression. Researchers will check if certain biological markers (like hormone levels and blood pressure) predict who responds better to enoxolone versus a placeb…

This study looks at whether changes in RNA editing can help predict how well people with depression respond to treatment. Researchers at Mayo Clinic will follow 120 adults with unipolar or bipolar depression to track RNA patterns and depression scores. The goal is to better under…